Protein Info for CA265_RS21070 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: transcription-repair coupling factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1112 transmembrane" amino acids 33 to 52 (20 residues), see Phobius details PF17757: UvrB_inter" amino acids 144 to 230 (87 residues), 77.8 bits, see alignment 1.6e-25 TIGR00580: transcription-repair coupling factor" amino acids 238 to 1043 (806 residues), 929.9 bits, see alignment E=1.1e-283 PF02559: CarD_TRCF_RID" amino acids 437 to 493 (57 residues), 63.6 bits, see alignment 4.5e-21 PF00270: DEAD" amino acids 562 to 722 (161 residues), 76.8 bits, see alignment E=5.1e-25 PF04851: ResIII" amino acids 562 to 718 (157 residues), 25.5 bits, see alignment E=3.3e-09 PF00271: Helicase_C" amino acids 762 to 866 (105 residues), 65.4 bits, see alignment E=1.6e-21 PF03461: TRCF" amino acids 972 to 1062 (91 residues), 81.1 bits, see alignment E=1.8e-26

Best Hits

KEGG orthology group: K03723, transcription-repair coupling factor (superfamily II helicase) [EC: 3.6.4.-] (inferred from 54% identity to cao:Celal_1876)

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.-

Use Curated BLAST to search for 3.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZAV0 at UniProt or InterPro

Protein Sequence (1112 amino acids)

>CA265_RS21070 transcription-repair coupling factor (Pedobacter sp. GW460-11-11-14-LB5)
MNIRDLINRYKTDDRVTQFTKALNSSKNPKIQLKGLVGSADAIVALSSYFLLHKPILFVL
PDREEAAYFQSDLESVLDKQVLLFPSSYRKSFDFTQVDTANVLARAEVLNELNHDSEYGK
IVVSYPEAIAEKVIDRSALEKNTLEISLGAKLGIDFINEFLIDYDFDRRDFVYEPGQFSI
RGGIVDIFSFSSDLPYRIEFFGDEVESIRSFEIESQLSVEDVKSLTIVPNVQAKFLTESN
ISILDYIDQDTQLWFKDVEFTLDIIKAGFKKAVELWKALPAADKNQNPEWIDPKFAFTDE
KLLGDHLQDFPIIEFGKQFFYKTDDRFEFETKPQPSFNKDFNLLIHNLKENEKEGIVNFI
FTDSPKQIERLYAILEDIDKTAKFTPINSMLREGFVDPQIQTAFYTDHQIFDRYYKYKLK
KGYQKSQAITLKDLRELKSGDYVTHIDHGIGKYAGLEKVEVNGKTQEMIRLIYADNDLLY
VNINSLNRIAKYSGKESGVPKMNKLGTDAWDKLKKTTKKKVKDIARDLIKLYALRKTQAG
TAFSPDSYLQTELEASFIYEDTPDQLKATQDVKKDMESPHPMDRLVCGDVGFGKTEIAVR
AAFKAVAEGKQAAILVPTTILALQHFKTFSSRLKDFPVTVDYINRFKTSKQIKDTLAEAA
AGKVDILIGTHRLLSKDVKFKDLGIMIIDEEQKFGVTAKERLKAVRVNVDTLTLTATPIP
RTLHFSLMGARDLSIISTPPPNRQPVSTELHVFNDKLIQEAVQFELDRGGQVFFIHNRVN
DLMQLGGLIQKLVPKARIGIAHGQLDGDQLEDVMLDFINGEKDVLVATTIIEAGLDIPNA
NTIIINHAHMFGLSDLHQMRGRVGRSNKKAFCYLLSPPLSTLTSEARKRLSAIEEFSDLG
SGFNVAMRDLDIRGSGNLLGAEQSGFIAEIGFEMYHKILDEAIQELKEAEFKGLFENEPA
RPFVGFTQVDTDLELYIPDAYITNITERYNLYTELSKLDNEAELAIFEKHLADRFGPVPS
QVKTMLSVVRLQWLGKKLGFEKISFKKNSLRGYFLSDKQSAYFDSNTFTRILTFAQNHPR
MCNLKEVKNTLRIAFDNISTVEEAIETLELID