Protein Info for CA265_RS21005 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: peptidase M41

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 671 transmembrane" amino acids 29 to 48 (20 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details PF06480: FtsH_ext" amino acids 30 to 138 (109 residues), 46 bits, see alignment E=1.1e-15 TIGR01241: ATP-dependent metallopeptidase HflB" amino acids 161 to 649 (489 residues), 710.9 bits, see alignment E=4.3e-218 PF00004: AAA" amino acids 251 to 383 (133 residues), 152.7 bits, see alignment E=1.6e-48 PF17862: AAA_lid_3" amino acids 408 to 449 (42 residues), 54.6 bits, see alignment 1.2e-18 PF01434: Peptidase_M41" amino acids 465 to 646 (182 residues), 200.6 bits, see alignment E=4.8e-63

Best Hits

KEGG orthology group: K03798, cell division protease FtsH [EC: 3.4.24.-] (inferred from 69% identity to phe:Phep_0030)

Predicted SEED Role

"Cell division protein FtsH (EC 3.4.24.-)" in subsystem Bacterial Cell Division (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z9T1 at UniProt or InterPro

Protein Sequence (671 amino acids)

>CA265_RS21005 peptidase M41 (Pedobacter sp. GW460-11-11-14-LB5)
MNDNQNTNEKQGKRIPNIPKKPQKGSKFNIFWVYAAIIIAIIAAQFLFTTDGGKEVTYQK
FEQQMLLKGDVQKVVAYKSDDLVRVEVYIKKDSLKKPAYDAYKSTSTFSVNNTASPVVFF
NAGTMDGLDKQLADSQKDLPANQPRVLAEKTSRSNPLASWFLSIILPVLLLIGFWIFMMR
RMGGGAGGGGQIFSIGKSKATLFDKESQVNITFNDVAGLEEAKTEVMEIVDFLKNPKKYT
DLGGKIPKGALLVGSPGTGKTLLAKAVAGEAQVPFFSLSGSDFVEMFVGVGASRVRDLFK
QAKDKSPCIIFIDEIDAIGRARGKNGVMGGNDERENTLNQLLVEMDGFGTNTHVIILAAT
NRADVLDKALLRAGRFDRQIYVDLPDVIERKQIFEVHITPLKKSEELDTEFLAKQTPGFS
GADIANVCNEAALIAARKNKSAVDKQDFLDAVDRIVGGLEKKNKIITPSEKRAIAIHEAG
HATVSWLLEHAAPLVKVTIVPRGQSLGAAWYLPEERLIVRPHQMLDEMCATMGGRAAEKV
MFDTISTGALSDLEKVNKQARAMVTIYGLNEKLGNITYYDSSGQNEYNFSKPYSEDTALT
IDKEISALIEGQYQRAINLLEENKDKLIQLADILIEKEVLFKDDLEVIFGKRLFENQGES
GTPGHITPVEA