Protein Info for CA265_RS19160 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: glutamine--fructose-6-phosphate transaminase (isomerizing)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01135: glutamine-fructose-6-phosphate transaminase (isomerizing)
  • amino acids 2 to 612 (611 residues), 841.9 bits, E=1.5e-257
• PF13522: GATase_6
  • amino acids 64 to 194 (131 residues), 84.5 bits, E=1e-27
• PF13537: GATase_7
  • amino acids 73 to 197 (125 residues), 66.1 bits, E=4.5e-22
• PF01380: SIS
  • amino acids 293 to 419 (127 residues), 116.8 bits, E=8.9e-38
  • amino acids 465 to 594 (130 residues), 99.6 bits, E=1.9e-32

Best Hits

Swiss-Prot: 64% identical to GLMS_BACTN: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (glmS) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K00820, glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC: 2.6.1.16] (inferred from 86% identity to phe:Phep_0131)

Predicted SEED Role

"Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 2.6.1.16)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (8/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (3/5 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis II (3/6 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis III (2/6 steps found)
• chitin biosynthesis (4/9 steps found)
• CMP-legionaminate biosynthesis I (2/10 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (8/24 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (11/33 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glutamate metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.16

Sequence Analysis Tools

See A0A1X9Z9Y0 at UniProt or InterPro

Protein Sequence (612 amino acids)

>CA265_RS19160 glutamine--fructose-6-phosphate transaminase (isomerizing) (Pedobacter sp. GW460-11-11-14-LB5)
MCGIVGYIGYREAWPIVLKGLKRLEYRGYDSAGIALMNNSGQHIYKKAGKVAVLEEFAEA
HDKSGTSGMGHTRWATHGVPSDRNSHPHTSNNGKLSIIHNGIIENYATLKEELTNRGHEF
KSDTDTEVLIHLIEEIQEIENIDLLEAVRLALREVNGAYAIVIMDKEHPDRLIAARKGSP
MVIGVGNGEYFIASDATPIIEYTKNVIYLKDGEIALMTREDLLIKQLDNVVQTPLIQELE
LKLEMLEKGGFDHFMLKEIYEQPRSIKDCMRGRIYPEEGKVQLGGIKEFAEKLKNIDRII
IVACGTSWHAGLVGEYLIEEYARIPVEVEYASEFRYRNPIITEKDVVIAISQSGETADTM
AAIEMAKERGATIFGICNVAGASIPRLTHAGVYTHAGPEIGVASTKAFTAQVTVLTLMAF
YMAQQKGTITTSKLIELLTELDNIPEKIQVALESNDLIKEVAEKIKDSTNCLFLGRGSGF
PVALEGALKLKEISYIHAEGYPAAEMKHGPIALIDEEMPVVFIATQNSSYEKVISNIQEV
KARKGKVIAIVTQGDTEVKKMADYCIEIPDANEAFLPLIATIPLQLLSYHIAVMRGCNVD
QPRNLAKSVTVE