Protein Info for CA265_RS18025 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: crossover junction endodeoxyribonuclease RuvC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 55% identical to RUVC_CYTH3: Crossover junction endodeoxyribonuclease RuvC (ruvC) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)

KEGG orthology group: K01159, crossover junction endodeoxyribonuclease RuvC [EC: 3.1.22.4] (inferred from 81% identity to phe:Phep_0400)

Predicted SEED Role

"Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4)" in subsystem DNA-replication or RuvABC plus a hypothetical (EC 3.1.22.4)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.22.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZCP6 at UniProt or InterPro

Protein Sequence (195 amino acids)

>CA265_RS18025 crossover junction endodeoxyribonuclease RuvC (Pedobacter sp. GW460-11-11-14-LB5)
MLNEKKERVIMGIDPGTAVMGYGVILEKGNKTELISLGVVKMTHLDDPFLKLQRIFEKTV
VLIDQYKPDVLAIEAPFYGKNIQVLLKLGRAQGIAIAAALSRNISVTEYSPRKIKQSITG
SGNATKEQVAAMLQRLLNFKETPEFLDATDGLAVAVCHSFQKITTGGKSKNYSGWESFVS
DNKTKVKGLAVKVKK