Protein Info for CA265_RS15610 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: bacillithiol biosynthesis cysteine-adding enzyme BshC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 528 PF10079: BshC" amino acids 1 to 525 (525 residues), 629.8 bits, see alignment E=2.1e-193 TIGR03998: bacillithiol biosynthesis cysteine-adding enzyme BshC" amino acids 14 to 524 (511 residues), 470.5 bits, see alignment E=4.2e-145

Best Hits

Swiss-Prot: 47% identical to BSHC_FLAPJ: Putative cysteine ligase BshC (bshC) from Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)

KEGG orthology group: None (inferred from 62% identity to phe:Phep_3526)

Predicted SEED Role

"FIG00907876: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z7P1 at UniProt or InterPro

Protein Sequence (528 amino acids)

>CA265_RS15610 bacillithiol biosynthesis cysteine-adding enzyme BshC (Pedobacter sp. GW460-11-11-14-LB5)
MQAKYISYQETGSFSKLVLDYINDEEQLKAFYSYRPDMEGLAKAIEHRNFSGNRETLVKV
LQDQYQHLQPNKSVTKNIELLGSANTFTVTTGHQLNLFTGPLYFIYKIVTTINLAIELKM
AHPDQNFVPVYWMATEDHDFDEINHVSVDEKNISWIQQTNGATGRLSTQTVAAAVTAYKG
YLGISKNGKRIAKLVEQAYLQHDNLADATRFLVNNLFEKYGLVIVNADDAQLKKQFTHII
TEDIIQHNSSKNIEKSSKNLEDLGYKTQVNGRDINFFYLIDNLRERLIFENGKYLVNHTD
ISFTEETLKAEIEAHPERFSPNVVMRPMYQEVILPNLAYIGGGAEVAYWMQLKANFDFYQ
VDFPVLLLRNSALLIDKRSAQNLYHLGFSLEDIFLPVEELKNIWVKRNTTALLSLADETR
AINSIFDQIKLNAYKIDKTLSVSTDTAKQRTNHLLANLEKKLFRAEKRKHETALLQIDNV
KKRLFPNGTLQERILNIAPMYVNYGEDFLSSCIENFEPLGGDFTVLLP