Protein Info for CA265_RS15090 in Pedobacter sp. GW460-11-11-14-LB5
Annotation: NAD kinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 51% identical to NADK_CYTH3: NAD kinase (nadK) from Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
KEGG orthology group: K00858, NAD+ kinase [EC: 2.7.1.23] (inferred from 76% identity to phe:Phep_0983)Predicted SEED Role
"NAD kinase (EC 2.7.1.23)" in subsystem NAD and NADP cofactor biosynthesis global (EC 2.7.1.23)
MetaCyc Pathways
- cytosolic NADPH production (yeast) (4/5 steps found)
- NADP biosynthesis (1/1 steps found)
- superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) (6/8 steps found)
- NAD phosphorylation and dephosphorylation (2/3 steps found)
- NAD phosphorylation and transhydrogenation (1/2 steps found)
- mitochondrial NADPH production (yeast) (3/5 steps found)
- NAD(P)/NADPH interconversion (3/6 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.7.1.23
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A1X9Z6N3 at UniProt or InterPro
Protein Sequence (293 amino acids)
>CA265_RS15090 NAD kinase (Pedobacter sp. GW460-11-11-14-LB5) MRIAIYGRDFNDTVLPYVQEVFNHLAEHHIQPVLYSKFKTSLHGKIKLPANTVIFHNHTE LKELADVLLSLGGDGTLLDTLSLIRNSGIPVIGINFGRLGFLASINKNEIASALKALINK EYTLDSRSLLTLESDNGLFGEENFALNDITIHRRDNSAMMIIHASMNDEFINSYWADGLI IATPTGSTAYSLSCGGPIIYPDSENFVITPIAPHNLNVRPVILPDDNKLSFEVEARESKF LVSCDSRTVTVERSVKISIKKADFCVNLIRLNNETYLNTLRNKLLWGIDTRNY