Protein Info for CA265_RS14765 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: alkaline phosphatase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 552 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF01663: Phosphodiest" amino acids 44 to 491 (448 residues), 177.7 bits, see alignment E=2.5e-56

Best Hits

Swiss-Prot: 54% identical to CDA_MYROD: Calcium-transporting ATPase (cda) from Myroides odoratus

KEGG orthology group: None (inferred from 65% identity to phe:Phep_1165)

Predicted SEED Role

"Alkaline phosphatase (EC 3.1.3.1); Type I phosphodiesterase/nucleotide pyrophosphatase precursor" (EC 3.1.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.1

Use Curated BLAST to search for 3.1.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z734 at UniProt or InterPro

Protein Sequence (552 amino acids)

>CA265_RS14765 alkaline phosphatase family protein (Pedobacter sp. GW460-11-11-14-LB5)
MKKISCLIFTISIFSISLSSAQTKKPATATAKAFPAEVARPKLVVGLVVDQMRWDYLYRY
YNRYSNGGFKRLINEGFSVENTFIPYTPTYTACGHTCIYTGSVPAVHGIIGNDWYDPETK
KNVYCTEDSSVTTVGSTPSSEGNMSPKNMLTTTITDELRLATNFRGKVIGISLKDRGSIL
PAGHAANAAYWYQGSTGNWITSTYYMKEVPTWIADYNKLKLANKFYAKNWETLYPMNTYV
NSTADEKAYEGKSSTFPHQLTQNIDKNFDAIRSTPYGNTITLDLAKLAILSEDLGQDNIT
DFLAVSCSSTDYVGHAYGPNSVEAEDTYLRLDKDFEEFFNYLDKKVGKGNYTVFLTADHG
AAHVPGFMQENKLPSGVVSDRDIANKLNAYLNDKFKVNNVVLKSMNNQIIFDHDKTDKGN
VSFDVIKSASVEFLKRLDGFQNAVDIAKISQSTIQEIQKKMITNGYNARRSGDIYYVLAP
NWFNGGSTGTTHGNWNPYDSHIPLVFMGWGIKAGASNKTHYMTDIAPTLAALLHIQMPNG
TVGEPITEITNK