Protein Info for CA265_RS13105 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: protein translocase subunit SecDF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 993 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 25 to 26 (2 residues), see Phobius details amino acids 517 to 536 (20 residues), see Phobius details amino acids 542 to 564 (23 residues), see Phobius details amino acids 570 to 588 (19 residues), see Phobius details amino acids 615 to 634 (20 residues), see Phobius details amino acids 640 to 664 (25 residues), see Phobius details amino acids 698 to 715 (18 residues), see Phobius details amino acids 820 to 838 (19 residues), see Phobius details amino acids 845 to 867 (23 residues), see Phobius details amino acids 881 to 900 (20 residues), see Phobius details amino acids 935 to 954 (20 residues), see Phobius details amino acids 960 to 984 (25 residues), see Phobius details PF07549: Sec_GG" amino acids 74 to 89 (16 residues), 16 bits, see alignment (E = 1.4e-06) amino acids 719 to 740 (22 residues), 29 bits, see alignment (E = 1.1e-10) TIGR01129: protein-export membrane protein SecD" amino acids 76 to 663 (588 residues), 380.1 bits, see alignment E=2.1e-117 PF21760: SecD_1st" amino acids 177 to 235 (59 residues), 61.8 bits, see alignment 6.5e-21 TIGR00916: protein-export membrane protein, SecD/SecF family" amino acids 427 to 657 (231 residues), 233.4 bits, see alignment E=4e-73 PF02355: SecD_SecF" amino acids 502 to 660 (159 residues), 76.1 bits, see alignment E=5e-25 amino acids 797 to 987 (191 residues), 171.9 bits, see alignment E=2.1e-54 PF03176: MMPL" amino acids 503 to 658 (156 residues), 28.9 bits, see alignment E=1.1e-10 TIGR00966: protein-export membrane protein SecF" amino acids 719 to 978 (260 residues), 198 bits, see alignment E=3.3e-62

Best Hits

KEGG orthology group: K12257, SecD/SecF fusion protein (inferred from 54% identity to shg:Sph21_2971)

Predicted SEED Role

"Protein-export membrane protein SecD (TC 3.A.5.1.1) / Protein-export membrane protein SecF (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZCR7 at UniProt or InterPro

Protein Sequence (993 amino acids)

>CA265_RS13105 protein translocase subunit SecDF (Pedobacter sp. GW460-11-11-14-LB5)
MQGKGFIKFIAIVLAIVCAYALSFTLVASKVEKDAKNAAKGDLAKEKAYLDSMSTVKVYP
VVGFTYQEVKAKEINLGLDLKGGMNVTMEISLAELVKSLAGNPTDANFNKAVQNAQIQLN
AGGKDYIKIFVDEFEKLSPGVKLADYFSNQDNASQLKPSASNSDVESFLEKEATSAIDRS
FTVLRSRIDGFGVVSPNMQKQEGSNRILIEMPGVQDKERIAKLLQGSAELQFWQVYQVQE
VAPLLENINKILAATLKTDAPATKDTTAAPAAGGKLAGLEKAATKDTTAKGGKLAGLGKK
DTSAVKAELIKSNPLYAVLNLPIYQGENGQQQLMPGAVVGMSLQKDTAKVNAYLKLPEVA
ASIPSTMKFMWSVKPREGSKIFELYAIKVVSADGKPDLGGEAISDSRADFDQKGKPEVTM
YMTSEGSAKWKKITAEAAADQNNKKSIAIVLDNQVYSAPTVQNEIAGGVSSITGNFTQAD
TKDLSNILKAGKLPAPARIAGSYVVGPTLGAQAIHDGLISFVIAFIVILIFMALYYHRAG
WVANFALLINLFFIIGILVSLGAVLTLPGIAGIVLTIGLSVDANILIFERVREELAHGKN
TATAIKEGFKHAMPSIIDSNVTLFILGAILYVFGSGPVQGFATTLCIGILSSLFAAVAIS
RVVFESLLNRKIDVSFDNSITRNAFKNISFNFVGRRKIYYVISTIIIIAGIGMYFKNGGL
NLGVDFKGGRTYLVHFDKAVNTEDLKAKLNPVFGNETPEVKTAGEDSQVKITTTFHIEDQ
DIKTDKVVEDALNKGLAGSKYEIVSSQKVTPIIASDIVNGAFYAVLISCLFMFIYIVVRF
KKWQYGLGAVIALFHDVLMVLSFYTILDGIMPFSLEIGQDFIAAILTVMGYTMTETVVVF
DRIREKLKESGKEDLHGEARNNLINFALNSTLSRTILTSLTVFFVLLVIFIFGGDSIRGF
IFALLIGRIIGTYSSLCISTPIVIDLGSSAEKK