Protein Info for CA265_RS12925 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: glycoside hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 41 to 61 (21 residues), see Phobius details PF01183: Glyco_hydro_25" amino acids 101 to 276 (176 residues), 165.1 bits, see alignment E=1.1e-52

Best Hits

Swiss-Prot: 43% identical to YEGX_ECOL6: Uncharacterized protein YegX (yegX) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K07273, lysozyme (inferred from 64% identity to phe:Phep_1439)

Predicted SEED Role

"Lyzozyme M1 (1,4-beta-N-acetylmuramidase) (EC 3.2.1.17)" (EC 3.2.1.17)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z5P3 at UniProt or InterPro

Protein Sequence (298 amino acids)

>CA265_RS12925 glycoside hydrolase (Pedobacter sp. GW460-11-11-14-LB5)
MPPEKRTPINKSPVARKPAARKPVARKPGANKKKKGALSVQLKLVIAALLLVLLSPFYYG
YVLRSFVATWRWVKDWGQDPNYRTYESFNIKIPKKYTVHGIDVSYYQGKINWQKVKEMKE
DEVSIRFAFIKATEGLMLVDPYFQRNWREAPKAGIICGAYHFFRPKKDGKTQAKFFLQVV
NIEKGDLPPVVDIESLDGVSPLKMRAELSDFLNYVEMKTKVRPIVYTGLKFYEDYLVDHF
EDYPLWIAHYYQPKLRMDKSRWKFWQHSDKAKINGIGHVVDFNAFNGDSLALDRLLVH