Protein Info for CA265_RS11205 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: hybrid sensor histidine kinase/response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1368 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details transmembrane" amino acids 797 to 815 (19 residues), see Phobius details PF07494: Reg_prop" amino acids 273 to 294 (22 residues), 18 bits, see alignment (E = 1e-06) amino acids 320 to 341 (22 residues), 17.5 bits, see alignment (E = 1.4e-06) amino acids 366 to 389 (24 residues), 20.6 bits, see alignment (E = 1.4e-07) amino acids 510 to 531 (22 residues), 16.5 bits, see alignment (E = 3e-06) amino acids 551 to 572 (22 residues), 20.3 bits, see alignment (E = 1.7e-07) PF07495: Y_Y_Y" amino acids 728 to 789 (62 residues), 46.9 bits, see alignment 8.6e-16 PF00512: HisKA" amino acids 845 to 910 (66 residues), 38 bits, see alignment 5.6e-13 PF02518: HATPase_c" amino acids 957 to 1065 (109 residues), 91.5 bits, see alignment E=1.9e-29 PF00072: Response_reg" amino acids 1118 to 1227 (110 residues), 91.9 bits, see alignment E=1.2e-29 PF12833: HTH_18" amino acids 1284 to 1362 (79 residues), 71 bits, see alignment 3.5e-23 PF00165: HTH_AraC" amino acids 1323 to 1360 (38 residues), 36.9 bits, see alignment (E = 1.2e-12)

Best Hits

Predicted SEED Role

"DNA-binding response regulator, AraC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z4M8 at UniProt or InterPro

Protein Sequence (1368 amino acids)

>CA265_RS11205 hybrid sensor histidine kinase/response regulator (Pedobacter sp. GW460-11-11-14-LB5)
MLQRDILDRRKLAKRLPGFGRYLLTAILVLCVFSKLHAQINGRHFRNISVEKGLSQSTVF
AIKQDTLGFIWIGTQDGLNRYDSKGFKVYRPVKSDPKSVQSYYTRTLFIDHTGSLWVGGN
QGVSRYNYATDSFTNYKLPRSLGEWYVSSITEDPQHNIWATSVVGGVFKLTAGESQFKQV
NYDSFNTGIKRVVYVGSWKQNILIGTEVGLFKMTGPKNKLVKIDLGTDKPAINDVYIDGD
VFWVATEGDGLIQYHFETGEKKVFMHSPGGKSIADNNIRCVGKDTDGNIWLGTFKGLTIF
DLNTNTLENYYHQISQPYTISQNSVRCFFKDKQNGIWLGTFYGGINYYHKNDIKFNLLSQ
NTGRLSLNDEVVSAIKEDSKGNFWIGTNDKGLNYWNRATNNISYFSNNENNANSLSANNI
KAIAFDNDQNLLVGMHNGGLNILNPNTGNVKRYRHSENDPNSIAGDLVYGILKDYKNRIW
IGTRSGLDQFNPQSQTFTHIHLDKAGKRPSSDDITYLFEDSKHRIWIGTTNGVTLFYPDN
MLFGNDLNNQLRDDVISCITEDKKGRIWIGSREGLILYDENQQSFVTYKNRKDFIKGTIY
GLQPDNEGNIWVSTNRGLIRYNPEAKTSQAFDETDGLQNNQFNDYAFCKASDGMLLFGGI
KGLSYFYPSSIKQQPLPLKLTFTGLEVFNNSVTSGDETKILENHIDQSTQLEFAAEYKQF
TIHFNTFNYISANRTKYLYKLDGFDKDWQHTEDLKITYNNLRAGSYNFLIKAVGPNGEAS
AVRTLKIIISPPWYNATWFYLFVFIDLVGASYIAYRIIDQRIKALHQLKLERIDKEKVRY
INQVKMDFFTNVSHELRTPLTLILAPLEELIKKPSTDKVITKRHEMMLINAKRLYNLVDQ
LFEFRKTETGTRKLKVSKSDIVSFIHEVYESFKPLSDKNQVQYTYHSSEAKLSFYFDNDA
MEKILFNLLSNAFKYTGAHNKISVELSTQDNFAIITVTDTGVGISEDDIAKVFDRFYQVN
NQEMNLGSGVGLAFTKRLIELHHGSIKAESELGRGSKFTVSIPMADAVYQEDVKTENMRY
ELSIVPEEEAIAENNLMYADQSLTIGLNENDGQRSKLLLVDDNKEILDYLQDYFKESYEI
TIAFDGKMALDILENEQFDLIVSDVMMPELDGLHFCKRLKQNINTSHIPVILLTAKTEVN
QQIKGLEMGADDYITKPFSVEMLGAKIASLLKSRKRLKEYYGGSKEVVPQNLAFNTLDEE
FLKEAIAIVEKYLADSDFSVDKFSREIGMSRSNLYLKFKAITGESATDFIKRIRFSKAVE
LMQSKRYTIAQITYMCGFNSPSYFSTAFKQYYGCMPSEYLAREDEMER