Protein Info for CA265_RS09880 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: beta-ketoacyl-[acyl-carrier-protein] synthase II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF00109: ketoacyl-synt" amino acids 1 to 249 (249 residues), 189.1 bits, see alignment E=1.2e-59 TIGR03150: beta-ketoacyl-acyl-carrier-protein synthase II" amino acids 2 to 412 (411 residues), 549.4 bits, see alignment E=2.1e-169 PF02801: Ketoacyl-synt_C" amino acids 257 to 369 (113 residues), 117.3 bits, see alignment E=3.9e-38

Best Hits

Swiss-Prot: 52% identical to FABF_BACSU: 3-oxoacyl-[acyl-carrier-protein] synthase 2 (fabF) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 76% identity to phe:Phep_1611)

MetaCyc: 52% identical to beta-ketoacyl-acyl carrier protein synthase II (Bacillus subtilis subtilis 168)
Beta-ketoacyl-acyl-carrier-protein synthase II. [EC: 2.3.1.179, 2.3.1.41]

Predicted SEED Role

"3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.179)" (EC 2.3.1.179)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.179, 2.3.1.41

Use Curated BLAST to search for 2.3.1.179 or 2.3.1.41

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z3X5 at UniProt or InterPro

Protein Sequence (416 amino acids)

>CA265_RS09880 beta-ketoacyl-[acyl-carrier-protein] synthase II (Pedobacter sp. GW460-11-11-14-LB5)
MKRVVVTGLGAITPLGNTVEQFWQQILAGKSGIGPITKFDSSKFKTHFAGEVKDFNPEAY
LDKKEIKKFDLFTQYAIGSSDQAIKDSGLDFSAMSDDQLAEVGVIWATGNGGIGTFEAQL
EEFHAGDGTPRFSPFFIPKMIVDIAAGAISIRHKLRGPNYCTVSACASSNTAIINAFDTI
RLGKASIMIAGGSEAALTKSSVGGFNAAQALSKNNDNPQGASKPFDADRDGFVMSEGAGA
LVLEDLDHALARGAHIYAEIIGGGMAADAYHLTGTPPDGVGAALGMTKALKDAGITADKI
DYINAHATSTGLGDLSELQAINTVFKGLPVVIGATKSMTGHLLGAAGAVESVISILSIRD
NVIPPTINTKNLDENIPKGLNFVLGESIKKEINYVLNNTFGFGGHTASTIFKKYEA