Protein Info for CA265_RS09355 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: endonuclease V

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 PF04493: Endonuclease_5" amino acids 17 to 208 (192 residues), 206.4 bits, see alignment E=1.8e-65

Best Hits

Swiss-Prot: 38% identical to NFI_ANAVT: Endonuclease V (nfi) from Anabaena variabilis (strain ATCC 29413 / PCC 7937)

KEGG orthology group: K05982, deoxyribonuclease V [EC: 3.1.21.7] (inferred from 53% identity to psn:Pedsa_0643)

Predicted SEED Role

"Endonuclease V (EC 3.1.21.7)" in subsystem DNA repair, bacterial (EC 3.1.21.7)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.21.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z4I9 at UniProt or InterPro

Protein Sequence (233 amino acids)

>CA265_RS09355 endonuclease V (Pedobacter sp. GW460-11-11-14-LB5)
MYDHYSFEDAAAYQIELARQLRFKPLTKIETIAGADISFNKNSTTMYAGIVILTYPEMVL
KSFALETYETSFPYKAGFLGFKEVPALLKVWELIVDKPDVVVLDGNGILHPRRMGVASHF
GILANQSTIGCAKSLLHGKNHQPENTRYSTAEIKNNSGEMLGFALRTKINCESVYVSAGH
LITQDQSLEIIKKSIGNYRIPEPTRLAHNIVNDFRTGKLKAGFHKVSAPLTLF