Protein Info for CA265_RS08330 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: galactose-1-epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01263: Aldose_epim
  • amino acids 53 to 380 (328 residues), 317.7 bits, E=4.1e-99

Best Hits

KEGG orthology group: K01785, aldose 1-epimerase [EC: 5.1.3.3] (inferred from 65% identity to phe:Phep_2727)

Predicted SEED Role

"Aldose 1-epimerase (EC 5.1.3.3)" in subsystem Lactose and Galactose Uptake and Utilization or Maltose and Maltodextrin Utilization (EC 5.1.3.3)

MetaCyc Pathways

• D-galactose degradation I (Leloir pathway) (5/5 steps found)
• trehalose degradation VI (periplasmic) (1/2 steps found)

KEGG Metabolic Maps

• Glycolysis / Gluconeogenesis

Isozymes

Compare fitness of predicted isozymes for: 5.1.3.3

Use Curated BLAST to search for 5.1.3.3

Sequence Analysis Tools

See A0A1X9Z362 at UniProt or InterPro

Protein Sequence (383 amino acids)

>CA265_RS08330 galactose-1-epimerase (Pedobacter sp. GW460-11-11-14-LB5)
MKKKIFKALPFATLCLAISFTSCNPKSDKGAATTEQSDSSKYTSTIDGKSVNLYTLKNKQ
GASVSISNYGGRVVSLLVPDKNNKLTDVVLGYDSVGAYRKKGEPFFGALIGRYGNRIGKG
KFNLEGKEYTLQLNDGVNTLHGGTDGFFAKVWEAKQLDGQKLELSYVSNDGEAGYPGKLD
VKVTYTLTDDNALQIDYLATTDKTTVVNLTNHAYFNLNGEGNETILDHELTIDANAYTPV
DSTLIPTGKLQPVVGTAFDFNKAKTIGKSIEENDQQLKFGKGYDHNFVLTHHDGKTPVAI
VKSPVTGIIMEVYTVEPGLQFYSGNFLTGADKDGKGGKSYPHRSAFCLETQHFPDAPNHA
NFASTVLKPGETYKTSTTYKFLK