Protein Info for CA265_RS08120 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: copper homeostasis protein CutC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 PF03932: CutC" amino acids 6 to 204 (199 residues), 244.3 bits, see alignment E=4e-77

Best Hits

Swiss-Prot: 49% identical to CUTC_CHRVO: Copper homeostasis protein CutC (cutC) from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)

KEGG orthology group: K06201, copper homeostasis protein (inferred from 52% identity to cpi:Cpin_6564)

Predicted SEED Role

"Cytoplasmic copper homeostasis protein cutC" in subsystem Copper homeostasis: copper tolerance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z2Z6 at UniProt or InterPro

Protein Sequence (249 amino acids)

>CA265_RS08120 copper homeostasis protein CutC (Pedobacter sp. GW460-11-11-14-LB5)
MATGCLEVCANSYQSAVAAQNGGAKRVEFCDNLAEGGTTPSYAQISLAKKNLSIEVWPII
RPRGGDFLYSEIEFELMKEDIKICKSLNCEGIVTGILKADGTIDKERCAELIELAKPMEV
AFHRAFDMSNDMDQALEDLIELNIKRVLTSGGASSAILGAEKLAQLVKKANGRIIIMPGA
GINENNIKNLIDQTGATQFHASAKEFVPSKMEFRNTETKMGSIEDEYRYELTSEIKVKAL
IDCINEAVS