Protein Info for CA265_RS07195 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: glycoside hydrolase family 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 820 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 72 to 196 (125 residues), 38.6 bits, see alignment E=2.7e-13 PF00703: Glyco_hydro_2" amino acids 200 to 304 (105 residues), 42 bits, see alignment E=3.7e-14 PF02836: Glyco_hydro_2_C" amino acids 309 to 628 (320 residues), 84.9 bits, see alignment E=1.4e-27 PF16355: DUF4982" amino acids 649 to 710 (62 residues), 52.8 bits, see alignment 7.7e-18 PF18565: Glyco_hydro2_C5" amino acids 737 to 815 (79 residues), 35.3 bits, see alignment E=2.2e-12

Best Hits

KEGG orthology group: None (inferred from 70% identity to phe:Phep_2700)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z2S2 at UniProt or InterPro

Protein Sequence (820 amino acids)

>CA265_RS07195 glycoside hydrolase family 2 (Pedobacter sp. GW460-11-11-14-LB5)
MLKLFRYIVLFISLFNSQLLFAQQSVRLNNNWEFLKQDLGGIWEAVRPVGVGNPEAVPLW
QKVSLPHCVNAEDAVDPDVNYYQGPAWYRTQLNIENPYQNGRTILHFEGAGQKTEVYVYT
TKVGAHVGGYDEWTVDITEAVAAFQKTAVYQKQFKGKVPVSVRTDNSRDLEMIPSDLSDF
NVYGGIYRYLNLVYTPSLSVDKMFAKAEVDAQGKLGKLSVKARLYNPVGLKEATIQLKLI
DAAGKIVSKTEKKLNDLSADVDLWSLEIKKPQLWSTEKPVQYRLQYEVISAAGNYKGEEK
IGFRHIEFIEKGPFNLNGKRLLLRGTHRHEDHAGVAAAMTEGMIREEMQMMKDMGVNFIR
LGHYQQSRIVLNLCDSLGIMVWEEIPWCRGGLGGEVYKQQARRMLTNMVEQHFNHPAIII
WGMGNENDWPGDFPEFDKEKIRTFMKELNDLSHKLDKSRYTAIRRCDFCSDIVDVYSPSI
WAGWYRGAYTDYKKASEDEFAKVKRFLHVEWGGDSHALRHSENPDKALSKIKTGGSADER
AGDASLYGGAARISKDGDWSESYITNLIDWHLKEQETMPWLSGTAYWPFKDFSTPVRPDN
PVPYMNQKGVVERDFTKKEAYYVFQSYWTEKPMVHIYGHTWPIRWGDEGEEKMVKVYSNC
TDAEIFLNGKSFGSKKRNSQDYPAAGLRWNLPFVKGENTIKVIARKGKQIITDEIKFTYQ
TEKWTKPAKMELKKISQQDDVATMEVKLFDAKGVPCLDAINWITFGLTGDGKLIDNQGTS
SGSRKVQAYNGRAIIKVKLNKGQSAVSVVSEGLKTVFSTL