Protein Info for CA265_RS05455 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: endonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF03372: Exo_endo_phos" amino acids 25 to 267 (243 residues), 57.5 bits, see alignment E=8.6e-20

Best Hits

KEGG orthology group: K06896, (no description) (inferred from 59% identity to shg:Sph21_0801)

MetaCyc: 44% identical to mannan mannose-6-phosphatase (Bacteroides thetaiotaomicron)
3.1.3.-

Predicted SEED Role

"endonuclease/exonuclease/phosphatase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9ZCE9 at UniProt or InterPro

Protein Sequence (277 amino acids)

>CA265_RS05455 endonuclease (Pedobacter sp. GW460-11-11-14-LB5)
MKLLLTALLLSLTTLVVKAQQITIGTFNIRYDNPADSGNLWINRAPVVANLIRFHKFDVL
GIQEGLKNQLDDISNALPEYARYGKGRDDGKDGGEHSAVFYRKDRFKLLKSGDFWLSESP
DQPGKGWDATCCNRICSWVFLEDVQSKKKFYAFNVHYDHQGVVARKESSKLILKKIAEIA
GDAPALLTGDLNGGRDSEWYQRIATSGVLSDTHTKVKFPYANNSSSNGFRTPRGQTVIDH
IFISKQFTATRWGILTDTYFGKFPSDHFPVLAEVELK