Protein Info for CA265_RS04850 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: glycosyl hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF14873: BNR_assoc_N" amino acids 39 to 157 (119 residues), 51.8 bits, see alignment E=1.6e-17 PF13859: BNR_3" amino acids 195 to 465 (271 residues), 84.5 bits, see alignment E=1.9e-27 PF13088: BNR_2" amino acids 217 to 500 (284 residues), 96.1 bits, see alignment E=4.5e-31

Best Hits

Predicted SEED Role

"Sialidase (EC 3.2.1.18)" in subsystem Galactosylceramide and Sulfatide metabolism or Sialic Acid Metabolism (EC 3.2.1.18)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.18

Use Curated BLAST to search for 3.2.1.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z224 at UniProt or InterPro

Protein Sequence (525 amino acids)

>CA265_RS04850 glycosyl hydrolase (Pedobacter sp. GW460-11-11-14-LB5)
MLKSTEKNMKLIKIGAVLNLLLMLTTFTLQASPLKGLSITASSPVVPVLKGMDSNPLLRV
LIYIPEGDKEITFKKIAAKLNPAGLQSVEKIDVYFTDQEPLFSAKNKLTTINPIAVNMGI
EVNIKLKPGMYYIWFSAKLKDQADIDSKIEFHVNQMEDTNAKKYTVKEEGQGFVKRLGIA
VKKAGENGINTFRIPGIATTDKGSLITVYDIRYKNSGDLPGNIDVGMSRSTDGGKSWEPM
KVIMDMGEPNENNGVGDPAVLFDPVTKKIWVAALWSKGNRSIAGSKPGLSEDVTGQLVLV
SSDDDGLTWSAPKSITKNVKDPAWNLFFNGPGSGIAMADGKLVFAAQYWDENAMPHSTLL
YSADHGLSWKTEDGPKPNTTESQIIETTPGILMLNMRDNRGSFRSVATTADMGKTWVEHH
TSYNALPDPVCMASFIKAMVMVKGKEKEVVFFGNDNTQANRYNLTIKASLDLGESWNKKN
ELLVDDRKFYGYSSLTKIDDQTIGFFYEGLKDLYFVRIPVSEIVK