Protein Info for CA265_RS04095 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: nitrite reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03460: NIR_SIR_ferr
  • amino acids 47 to 112 (66 residues), 77.6 bits, E=7.2e-26
  • amino acids 321 to 386 (66 residues), 48.5 bits, E=8.8e-17
• PF01077: NIR_SIR
  • amino acids 122 to 277 (156 residues), 122.5 bits, E=1.7e-39
  • amino acids 396 to 541 (146 residues), 37.4 bits, E=2.6e-13
• PF05168: HEPN
  • amino acids 584 to 649 (66 residues), 22.9 bits, E=1.2e-08

Best Hits

KEGG orthology group: K00381, sulfite reductase (NADPH) hemoprotein beta-component [EC: 1.8.1.2] (inferred from 76% identity to phe:Phep_3092)

Predicted SEED Role

"Ferredoxin--sulfite reductase (EC 1.8.7.1)" (EC 1.8.7.1)

MetaCyc Pathways

• superpathway of L-methionine biosynthesis (by sulfhydrylation) (12/12 steps found)
• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (9/10 steps found)
• assimilatory sulfate reduction I (4/4 steps found)
• assimilatory sulfate reduction IV (4/4 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• assimilatory sulfate reduction II (2/3 steps found)

KEGG Metabolic Maps

• Selenoamino acid metabolism
• Sulfur metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.1.2 or 1.8.7.1

Sequence Analysis Tools

See A0A1X9Z1I7 at UniProt or InterPro

Protein Sequence (696 amino acids)

>CA265_RS04095 nitrite reductase (Pedobacter sp. GW460-11-11-14-LB5)
MQSFRTELENPIVEQDIIDLENKIKAFRDGTIHDEKFRSLRLARGVYGQRQPGVQMVRIK
LPFGKVTFKQLLRIADIADEYGSGNLHLTTRQDIQIHYVSLDRTPELWAKLEQDDITLRE
ACGNTVRNVTASPNAGIDAEEPFDVSPYAQAVFAYFLRNPICQEMGRKIKISFSSSDRDT
AFSYIHDLGFIPKINENGERGFKVLFAGGLGAQPFLANAVHEFLPEDQLIPFTESVLRVF
DRYGERTNRNKARLKYLVQKLGLEEVLRLVAEERIANKVKTFKIDINTVPQPLLPLEQEY
PAVEILNEAHYKHWLATNVIEQKQAGFYGVYVKVQVGDIKTDKARAFVDAIRLYVADEIR
ITQNQGLLLKFVRKEALPSLYSALNKIGFTTAGFDSLADITTCPGTDTCNLGISNSMTLA
EVLEEVIYTDFPEFIYEKNIKIKISGCMNSCGQHGLAEIGFHGSSVKAEGKVVPAVQVML
GGGTVGNGVGRVAERVIKVPSKRATSVLHFILNDFKANNLEEENFHQYYDRKGKDHFYQL
LKPLADLTNLKTEEFVDWGHVEEFVTAIGVGECAGVVIDLVATLLLEADEKFDWAKQNLE
KAAYADAIYHTYSTFVSAAKSLLLDKGVNSSTQVGVIREFDNHYVETGEFNLSTNFSDLV
LQINKNEPTAEFAQKYFEEAKQFLNQIKEKRAVLAK