Protein Info for CA265_RS03655 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: phosphoribosylpyrophosphate synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 TIGR01251: ribose-phosphate diphosphokinase" amino acids 16 to 271 (256 residues), 130.5 bits, see alignment E=3.1e-42 PF13793: Pribosyltran_N" amino acids 19 to 107 (89 residues), 38.2 bits, see alignment E=1.2e-13 PF00156: Pribosyltran" amino acids 137 to 254 (118 residues), 29.9 bits, see alignment E=3.3e-11

Best Hits

KEGG orthology group: K00948, ribose-phosphate pyrophosphokinase [EC: 2.7.6.1] (inferred from 72% identity to fjo:Fjoh_0755)

Predicted SEED Role

"Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)" in subsystem De Novo Purine Biosynthesis or Pentose phosphate pathway (EC 2.7.6.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.6.1

Use Curated BLAST to search for 2.7.6.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z0S5 at UniProt or InterPro

Protein Sequence (277 amino acids)

>CA265_RS03655 phosphoribosylpyrophosphate synthetase (Pedobacter sp. GW460-11-11-14-LB5)
MLNLNPGFTPLGENNLIEYKSFLFAGGEPHIKISNNFDAALPITITHRINSFNDLGLICI
TVDALKRMGVKEIHLFIPYFPAARQDRVMIPGEPLSVKVYADIINAMALANVTIFDPHSE
VSPALLNNCVTISNHEFIKQVIAKIGTDVKLISPDGGALKKIYKVSEFLDGAEVIECSKS
RDVKTGKLSGFKVYAEDLAGADCLIVDDICDGGGTFIGLSEALKAKNAGKLYLAISHGIF
SKGFDELDKYFEQIFTTDSIKEVDHKGVTQIKLQKIL