Protein Info for CA265_RS03365 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: molecular chaperone DnaK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 PF00012: HSP70" amino acids 19 to 604 (586 residues), 641.2 bits, see alignment E=1.5e-196 PF06723: MreB_Mbl" amino acids 129 to 380 (252 residues), 64.2 bits, see alignment E=9.8e-22

Best Hits

KEGG orthology group: K04044, molecular chaperone HscA (inferred from 82% identity to phe:Phep_3231)

Predicted SEED Role

"Chaperone protein DnaK" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z0X8 at UniProt or InterPro

Protein Sequence (618 amino acids)

>CA265_RS03365 molecular chaperone DnaK (Pedobacter sp. GW460-11-11-14-LB5)
MAKISINLATGSFQKEEIIVGIDLGTTNSLVAFINPDKNPQVINDAGKGILVPSVVYFNN
QNEAIVGNEAKEFLTTDPSNTIFSVKRLLGRSYKDVAEHKDIFSYKIIDDDSDALVKIHA
GDRFYTPIELSGEILKELKARAEHALKTPVNRAVITVPAYFNDSQRQATRDAGKLAGLDV
MRIVNEPTAASLAYGIGLDPTQQKTIAVYDLGGGTFDVSILQIQNGIFEVLATNGNTYLG
GDDFDRAILNYWLEKNNLDVAVVAQDNILMQTLRLQAEAAKKALSTQNLYNEQVGEIWCT
LDKQTFEQLISAKVEETITACKNALSDADLSASDIDEVILVGGSTRTPYVKQAVENFFGK
KPQDNINPDEVVALGAAIQADVLAGNRSDILLLDVTPLSLGIETMGGLMDVIIARNSKVP
TKAGRQYTTSIDGQVNMKISVYQGERDLVKENRKLAEFDLKGIPAMPAGLPKVDINFLLN
ADGILTVQAIELRSGVKQEIEITPSYGLSDDTVEKMLLDSIEHAKSDVEQRMLIEARSEG
EQLLYTAERFIEKHAEHLTETEIAETKVHIEALRTALATQEKDTILKRADELNEFTRPFA
ERVMDAAISTAMKGKKIE