Protein Info for CA265_RS02755 in Pedobacter sp. GW460-11-11-14-LB5

Annotation: phenylalanine--tRNA ligase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 799 TIGR00472: phenylalanine--tRNA ligase, beta subunit" amino acids 1 to 798 (798 residues), 826.4 bits, see alignment E=1.3e-252 PF01588: tRNA_bind" amino acids 48 to 152 (105 residues), 71.6 bits, see alignment E=1.2e-23 PF03483: B3_4" amino acids 221 to 394 (174 residues), 224.1 bits, see alignment E=2.3e-70 PF03484: B5" amino acids 415 to 480 (66 residues), 72.6 bits, see alignment E=6.3e-24 PF17759: tRNA_synthFbeta" amino acids 497 to 687 (191 residues), 127.3 bits, see alignment E=1.5e-40 PF03147: FDX-ACB" amino acids 705 to 798 (94 residues), 100.8 bits, see alignment E=1.1e-32

Best Hits

Swiss-Prot: 52% identical to SYFB_BACTN: Phenylalanine--tRNA ligase beta subunit (pheT) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K01890, phenylalanyl-tRNA synthetase beta chain [EC: 6.1.1.20] (inferred from 76% identity to phe:Phep_0825)

Predicted SEED Role

"Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20)" (EC 6.1.1.20)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.1.1.20

Use Curated BLAST to search for 6.1.1.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9Z0I3 at UniProt or InterPro

Protein Sequence (799 amino acids)

>CA265_RS02755 phenylalanine--tRNA ligase subunit beta (Pedobacter sp. GW460-11-11-14-LB5)
MKISYNWLKQFVQIDKTPQELSLILTNVGLEVESVEKVQPVVGGLEGLVIGEVLTCVQHP
NADRLRITTVNVGAKENLQIVCGAPNVGAGQKVVVATVGTTVYPLEGEPFKIKESKIRGE
LSQGMICAEDEIGLGKSHDGIMILAGDTEIGIPAKEHFKMDDDFVFEIGLTPNRADAASH
LGVARDLAAYFRSEYEMPDLLAFKTDNENLVIPVEVEDLAACPRYSSLTLSGVTVKESPE
WLKDKLKVIGLRPINNVVDITNYVLHGLGQPLHAFDADKITGGKVIVKKVAEGTPFVTLD
DVERKLNADDLMICNAEAPMCIAGVFGGKSSGVDASTKNIFLESAYFNSVSVRKTSKRHG
LKTDASFRFERGTDPEITVTALKYAALLIKELAGGEISSSVSDIYPSHIKPFEFEVSYSN
INKLIGANIPSAEIKHIITALGISATNTSDDTLALRVPSFKVDVTRECDITEEVLRIYGY
NNIEIPSKVNASLSYSIKPEKENTHNVIADMLTSNGYAEIMCNSLTKSAYSKNLDEAVFI
LNPLSSDLNVMRQNLLMPALESVAYNQNRKNADVKFYEFGKTYHLINEQYVERPRLLLLI
SGAKQSEQWNHNAKPATFYNLKSAVDAIISRLGIASYQSDVLNDENFAYGIKYFRGDKSL
VSFGAVSKADRKVADVNAEVFYADFDWAALLDIVRKNKIVNKEVSKYPQVRRDLSLLIDQ
AVTFDTLKSIAFKTDKKLIKEVGVFDVYVGDKLPEGKKSYALNFILQDEEQTLTDKQIEN
TMQKLIANLTAQAGAEIRK