Protein Info for BWI76_RS27890 in Klebsiella michiganensis M5al

Annotation: GntR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 PF00392: GntR" amino acids 3 to 65 (63 residues), 76.9 bits, see alignment E=1.5e-25 PF08220: HTH_DeoR" amino acids 29 to 61 (33 residues), 23.9 bits, see alignment 5.7e-09 PF07702: UTRA" amino acids 87 to 222 (136 residues), 113 bits, see alignment E=2.1e-36

Best Hits

Swiss-Prot: 79% identical to YIDP_ECOLI: Uncharacterized HTH-type transcriptional regulator YidP (yidP) from Escherichia coli (strain K12)

KEGG orthology group: K03482, GntR family transcriptional regulator, glv operon transcriptional regulator (inferred from 91% identity to kva:Kvar_0017)

Predicted SEED Role

"HTH-type transcriptional regulator YidP"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AV90 at UniProt or InterPro

Protein Sequence (248 amino acids)

>BWI76_RS27890 GntR family transcriptional regulator (Klebsiella michiganensis M5al)
MIYKSIADRLRLRLNSSDFEVGSPLPGEKKLAEEFGVARMTIRKAIDLLVAWGLVVRRHG
SGTYVARKDLHHETTNLTGLAEVLRKQGKEVISRVLVFEVMPAPPAIASLLRIQIDERIY
FSRRVRYVDGKPLMLEDSYMPVKLFRNLSLAHLEGSKFDYIEKECGLTISGNYETLSPVL
ADRQLAQSMNVPEQTPLLRITSLSYSDSGEFLNYSVMFRNASVYQVDYHLRRVRAENPLT
YPPEQHRQ