Protein Info for BWI76_RS27635 in Klebsiella michiganensis M5al

Annotation: AraC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 317 transmembrane" amino acids 98 to 116 (19 residues), see Phobius details PF01965: DJ-1_PfpI" amino acids 66 to 171 (106 residues), 27.9 bits, see alignment E=2.8e-10 PF12833: HTH_18" amino acids 233 to 311 (79 residues), 74.1 bits, see alignment E=1.3e-24 PF00165: HTH_AraC" amino acids 273 to 311 (39 residues), 26.9 bits, see alignment 6.1e-10

Best Hits

KEGG orthology group: None (inferred from 88% identity to eae:EAE_06680)

Predicted SEED Role

"Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BBG7 at UniProt or InterPro

Protein Sequence (317 amino acids)

>BWI76_RS27635 AraC family transcriptional regulator (Klebsiella michiganensis M5al)
MKLTEVAIVAVDGFSPFHYSVPCMLFGDTVSKTKRFNLHICAERPGLLSARDGFALNASG
DFSLLEQADIVVVPYWGAVNQRPPQSLLDGLVRARNNGAQIVGLCLGAFVLGYAGLLDDR
RAATHWEFEQDFQRLFPQVRLDINALYVDDEGIITSAGTAAALDCCLYLIRQRFGSLVAN
QIARRMIVPPHREGGQAQFIAQPVPKNTRDARINGLLEYLQQHIREPHNLDSLAQVAAMS
RRTLTRHFAKATGMGIADWLAAERLRRSQHLLEAGDLPVGQVAEEVGYRSAVTWRQQFKA
RFGVSPAEWRRTFRRGA