Protein Info for BWI76_RS27555 in Klebsiella michiganensis M5al

Annotation: putative sugar kinase/transcriptional regulator, ATPase domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 PF00480: ROK" amino acids 3 to 299 (297 residues), 242.2 bits, see alignment E=8.7e-76 PF02685: Glucokinase" amino acids 7 to 253 (247 residues), 29.8 bits, see alignment E=3.4e-11

Best Hits

KEGG orthology group: None (inferred from 67% identity to ecp:ECP_3755)

Predicted SEED Role

"ROK family Glucokinase with ambiguous substrate specificity"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BBY7 at UniProt or InterPro

Protein Sequence (310 amino acids)

>BWI76_RS27555 putative sugar kinase/transcriptional regulator, ATPase domain protein (Klebsiella michiganensis M5al)
MKYLGLDIGGSKIAAVVMDEQGHEWRRFRVETRKQTRQQFIATLVELITAIGDELAQPLA
IGIALPGSISPQSGKIRNANIQVINGCRLQDELEQRLGQSVVLANDGNCFALSEACDGAG
ADYSLVFGMTLGTGCGGGIALNRQIFPGASGIAAECGHITLPGYQEVNDGPPARCYCGKY
NCVESFISGTGLSARYRLLTQEALSSQAIIARALEGEHAACEQVLRFRQQLARTLATVVN
LIDPGVIILGGGLSNVALLVNDLEADVAPLVFTDHFITPIVPARHGDSSGMRGAAWLAVR
SGVENETFTD