Protein Info for BWI76_RS27170 in Klebsiella michiganensis M5al

Annotation: MltR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 transmembrane" amino acids 46 to 61 (16 residues), see Phobius details PF05068: MtlR" amino acids 29 to 187 (159 residues), 219.5 bits, see alignment E=1.3e-69

Best Hits

Swiss-Prot: 85% identical to MTLR_ECOL6: Mannitol operon repressor (mtlR) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02562, mannitol operon repressor (inferred from 92% identity to kva:Kvar_0157)

Predicted SEED Role

"Mannitol operon repressor" in subsystem Mannitol Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BBQ7 at UniProt or InterPro

Protein Sequence (198 amino acids)

>BWI76_RS27170 MltR family transcriptional regulator (Klebsiella michiganensis M5al)
MRQDLARSEPRPLLMSDMQAIMEETQAFENRVLERLNAGKTVRSFLIATVELLTEAVNIL
VLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVISRAEYEDAELLMALREEL
NHDGNEYSFTDDEILGPFGELHCVAALPPTPLFDESDADLLAMQKLRYQQVVRSTMMLSL
TELISKISLKKAFQKSTL