Protein Info for BWI76_RS27045 in Klebsiella michiganensis M5al

Annotation: XylR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 PF22177: PBP1_XylR" amino acids 7 to 104 (98 residues), 154.5 bits, see alignment E=1.9e-49 PF13377: Peripla_BP_3" amino acids 113 to 277 (165 residues), 128.6 bits, see alignment E=6.4e-41 PF00165: HTH_AraC" amino acids 294 to 334 (41 residues), 32.5 bits, see alignment 1.8e-11 amino acids 348 to 384 (37 residues), 46.9 bits, see alignment 5.5e-16 PF12833: HTH_18" amino acids 309 to 386 (78 residues), 71.4 bits, see alignment E=1.6e-23

Best Hits

Swiss-Prot: 88% identical to XYLR_ECOL6: Xylose operon regulatory protein (xylR) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 95% identity to eae:EAE_06145)

Predicted SEED Role

"Xylose activator XylR (AraC family)" in subsystem Xylose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BB81 at UniProt or InterPro

Protein Sequence (392 amino acids)

>BWI76_RS27045 XylR family transcriptional regulator (Klebsiella michiganensis M5al)
MFEKRHRITLLFNANKAYDRQVVEGVGEYLQASQLEWDIFIEEDFRARIENIKEWLGDGV
IADYDDPEIENLLIDVNVPIVGVGGSFHRPECYPPVHYIATDNAALVESAFLHLKEKGIN
RFAFYGLPASSCKGWAAEREHAFCQLVAREKYRGVVYQGLETAPENWQHAQNRLADWLQT
LPPQTGIIAVTDARARHVLQACERLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGTR
QMGYQAAKLLHRLLENEELPLQRQLIPPMRVVERRSTDYRSLTDPSVIQAMHYIRNHACK
GIKVEQVLDAVGISRSNLEKRFKEEVGETIHTVIHSEKLEKARSLLVSTTLSINEISQMC
GYPSLQYFYSVFKKEYDVTPKEYRDRHSEVMM