Protein Info for BWI76_RS26970 in Klebsiella michiganensis M5al

Annotation: aromatic acid/H+ symport family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 59 to 78 (20 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details amino acids 147 to 170 (24 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 253 to 274 (22 residues), see Phobius details amino acids 293 to 313 (21 residues), see Phobius details amino acids 322 to 339 (18 residues), see Phobius details amino acids 345 to 370 (26 residues), see Phobius details amino acids 382 to 404 (23 residues), see Phobius details amino acids 412 to 430 (19 residues), see Phobius details TIGR00895: MFS transporter, aromatic acid:H+ symporter (AAHS) family" amino acids 7 to 403 (397 residues), 445.4 bits, see alignment E=9.3e-138 PF07690: MFS_1" amino acids 29 to 281 (253 residues), 131.9 bits, see alignment E=5.6e-42 amino acids 260 to 432 (173 residues), 71.9 bits, see alignment E=9.8e-24 PF00083: Sugar_tr" amino acids 30 to 273 (244 residues), 100 bits, see alignment E=3.2e-32 PF06779: MFS_4" amino acids 48 to 204 (157 residues), 33.3 bits, see alignment E=7e-12

Best Hits

Swiss-Prot: 56% identical to PCAK_PSEPU: 4-hydroxybenzoate transporter PcaK (pcaK) from Pseudomonas putida

KEGG orthology group: None (inferred from 94% identity to eae:EAE_06070)

Predicted SEED Role

"4-hydroxybenzoate transporter" in subsystem Cinnamic Acid Degradation or Gentisare degradation or Phenylpropanoid compound degradation or Salicylate and gentisate catabolism or p-Hydroxybenzoate degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BB68 at UniProt or InterPro

Protein Sequence (452 amino acids)

>BWI76_RS26970 aromatic acid/H+ symport family MFS transporter (Klebsiella michiganensis M5al)
MKKTTIDIQAFINEHPFTKYQWMILALCFITVAMDGFDTAIIGFIASDLVQEWGVEKSAL
GPVMSAALVGLAVGALTAGPLADRVGRKKVLIMSIVVFGGFSLLTAFATSLNQLTLLRFL
TGLGLGAAMPNAATLMSEYAPERRRALMVNLMFVGFPMGSSLGGFLSAWMIPHYGWQSVL
VLGGVMPLLLAVVLIFLLPESARYMVVKRQPAQRIAAILRRIAPVPEQAEFELREAGQIQ
EKSSIGVIFSPRYAVGTIMLCLTYFMGLLIFYLLTSWLPLLIRETGATMSQASIITALFP
LGGGIGVLILGALMDKLNPNKVVAVGWLLTGVFVCLVGFSTHNLLLMGIMVFIAGSIMNG
AQSSMPALAAGFYPTQGRATGVAWMLGIGRFGGILGAFSGAFLMQAQLSFETIFSLLAIP
AFLSAIALLVKYKLGQRQPAASQGDVKKLQKA