Protein Info for BWI76_RS26830 in Klebsiella michiganensis M5al

Annotation: endoglucanase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01270: Glyco_hydro_8" amino acids 18 to 330 (313 residues), 325.7 bits, see alignment E=1.5e-101

Best Hits

Swiss-Prot: 82% identical to GUN_CELUD: Endoglucanase from Cellulomonas uda

KEGG orthology group: K01179, endoglucanase [EC: 3.2.1.4] (inferred from 82% identity to kpu:KP1_5232)

Predicted SEED Role

"Endoglucanase precursor (EC 3.2.1.4)" (EC 3.2.1.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.4

Use Curated BLAST to search for 3.2.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BB41 at UniProt or InterPro

Protein Sequence (334 amino acids)

>BWI76_RS26830 endoglucanase (Klebsiella michiganensis M5al)
MSLRALATVVVTTMMMLPHAWADTAWESYKSRFMMPDGRIIDTGNGNGNVSHTEGQGFAM
LLAVANNDRPAFDKLWQWTDKTLRNKEDGLFYWRYNPVAPNPVADKNDAADGDTLIAWAL
LRAQQQWHEKSYGSASDAITASLLKSTVVTFAGRQVMLPGAKGFYLNDHLNLNPSYFIFP
AWQAFAARTHLTAWRKLQSDGQALLGKMAWGTSQLPSDWVALRADGRMEPAKEWPTRMSF
DAIRIPLYVYWNDPKSSLLTPWKNWFQRYPRLQTPAWINVNTDEVAPWFMTGGLLAVRDL
TLGEAQAEPQISAQDDYYSASLKLLVWLANKDQS