Protein Info for BWI76_RS26610 in Klebsiella michiganensis M5al

Annotation: oligopeptidase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 680 PF19310: TOP_N" amino acids 46 to 148 (103 residues), 95.7 bits, see alignment E=1.8e-31 PF01432: Peptidase_M3" amino acids 222 to 677 (456 residues), 586.4 bits, see alignment E=6.1e-180

Best Hits

Swiss-Prot: 93% identical to OPDA_SALTY: Oligopeptidase A (prlC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 95% identity to eae:EAE_05800)

MetaCyc: 93% identical to oligopeptidase A (Escherichia coli K-12 substr. MG1655)
Oligopeptidase A. [EC: 3.4.24.70]

Predicted SEED Role

"Oligopeptidase A (EC 3.4.24.70)" in subsystem Protein degradation (EC 3.4.24.70)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BAV7 at UniProt or InterPro

Protein Sequence (680 amino acids)

>BWI76_RS26610 oligopeptidase A (Klebsiella michiganensis M5al)
MTNPLLTPFSLPPFSAIKPEHVVPAVTKALDDCRAAVERAVAQGAPYTWENLCQPLAEVD
DVLGRLFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQHEGLYKAYRDLRDGDHYA
TLNTAQKKAVDNALRDFELSGIGLAKEQQKRYGEIAARLSELGNQYSNNVLDATMGWTKL
IADESELSGMPESALAAAKAQAEAKELQGYLLTLDIPSYLPVMTYCDNQALREELYRAYS
TRASDQGPNAGKWDNGPVMAEILALRHELAQLLGFDSYADKSLATKMAENPQQVLDFLTD
LAKRARPQGEKELAQLRAFAKAECGVDELQPWDIAYYSEKQKQHLYSISDEQLRPYFPEN
KAVNGLFEVVKRIYGITAKERTDVDVWHPEVRFFELYDDKNELRGSFYLDLYAREHKRGG
AWMDDCVGQMRKLDGTLQKPVAYLTCNFNRPVSGKPALFTHDEVITLFHEFGHGLHHMLT
RIDTAGVSGISGVPWDAVELPSQFMENWCWEPEALAFISGHYETGEPLPQELLEKMLAAK
NYQAAMFILRQLEFGLFDFRLHAEFSPQQGAKILETLAEIKQQVALIPGPSWGRFPHAFS
HIFAGGYAAGYYSYLWADVLAADAFSRFEEEGIFNRETGQSFLDNILSRGGSEEPMVLFK
RFRGREPQLDAMLEHYGIKS