Protein Info for BWI76_RS26305 in Klebsiella michiganensis M5al

Annotation: sn-glycerol-3-phosphate ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF01547: SBP_bac_1" amino acids 38 to 337 (300 residues), 120.6 bits, see alignment E=1.4e-38 PF13416: SBP_bac_8" amino acids 44 to 355 (312 residues), 139.1 bits, see alignment E=2.5e-44

Best Hits

Swiss-Prot: 93% identical to UGPB_SALTI: sn-glycerol-3-phosphate-binding periplasmic protein UgpB (ugpB) from Salmonella typhi

KEGG orthology group: K05813, sn-glycerol 3-phosphate transport system substrate-binding protein (inferred from 97% identity to kva:Kvar_0287)

MetaCyc: 90% identical to sn-glycerol 3-phosphate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-34-RXN [EC: 7.6.2.10]; 7.6.2.10 [EC: 7.6.2.10]

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BAZ6 at UniProt or InterPro

Protein Sequence (438 amino acids)

>BWI76_RS26305 sn-glycerol-3-phosphate ABC transporter substrate-binding protein (Klebsiella michiganensis M5al)
MISLRHTALGLALSLAFAGQALAVTTIPFWHSMEGELGKEVDSLAQRFNAANPDYKIVPV
YKGNYEQSLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIKPVYQVFSDAGIQFDETQF
VPTVSGYYTDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLAAYTAKLK
AAGMKCGYASGWQGWIQIENFSAWHGLPVATKNNGFDGTDAVLEFNKPEQVKHIALLAEL
NKKGDFSYFGRKDESTEKFYNGDCAITTASSGSLADIRQYAKFNYGVGMMPYDADVKGAP
QNAIIGGASLWVMQGKDKETYTGVAKFLDFLTKPENAAEWHQKTGYLPITTAAYNLTREQ
GFYDKNPGADIATRQMLNKPPLPFTKGLRLGNMPQIRTIVDEELESVWTGKKTPQQALDA
AVERGNQLLRRFEQSTKS