Protein Info for BWI76_RS26295 in Klebsiella michiganensis M5al

Annotation: glycerol-3-phosphate transporter membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 81 to 105 (25 residues), see Phobius details amino acids 112 to 131 (20 residues), see Phobius details amino acids 145 to 166 (22 residues), see Phobius details amino acids 190 to 210 (21 residues), see Phobius details amino acids 216 to 238 (23 residues), see Phobius details amino acids 250 to 272 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 92 to 276 (185 residues), 71.4 bits, see alignment E=4.4e-24

Best Hits

Swiss-Prot: 95% identical to UGPE_SALTY: sn-glycerol-3-phosphate transport system permease protein UgpE (ugpE) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K05815, sn-glycerol 3-phosphate transport system permease protein (inferred from 94% identity to ent:Ent638_3854)

MetaCyc: 89% identical to sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE (Escherichia coli K-12 substr. MG1655)
ABC-34-RXN [EC: 7.6.2.10]; 7.6.2.10 [EC: 7.6.2.10]

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, permease protein UgpE (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BB87 at UniProt or InterPro

Protein Sequence (281 amino acids)

>BWI76_RS26295 glycerol-3-phosphate transporter membrane protein (Klebsiella michiganensis M5al)
MIENRRGLTIFSHTMLILGIAVILFPLYVAFVAATLDSKAVFDTPMTLIPGGHLLENMKF
IWVNGVGANSAPFWLMMLNSFIMAFGITVGKITVSMLSAFAIVWFRFPLRNLFFWMIFIT
LMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELIEAARID
GASPMRFFRDIVLQLSKTNLAALFVITFIYGWNQYLWPLLIITDVNLGTAVAGIKGMIAI
GQGTTQWNQVMAAMLLTLIPPVVIVLAMQRAFVRGLVDSEK