Protein Info for BWI76_RS25485 in Klebsiella michiganensis M5al

Annotation: septum formation protein Maf

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00172: septum formation protein Maf
  • amino acids 2 to 182 (181 residues), 222 bits, E=2.2e-70
• PF02545: Maf
  • amino acids 4 to 184 (181 residues), 209.6 bits, E=1.7e-66

Best Hits

Swiss-Prot: 88% identical to NTPPA_SALTY: dTTP/UTP pyrophosphatase (yhdE) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 93% identity to eae:EAE_04650)

MetaCyc: 84% identical to nucleoside triphosphate pyrophosphatase YhdE (Escherichia coli K-12 substr. MG1655)
Nucleotide diphosphatase. [EC: 3.6.1.9]; 3.6.1.9 [EC: 3.6.1.9]

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (18/18 steps found)
• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (14/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis I (9/9 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (7/7 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis III (8/9 steps found)
• pyrimidine deoxyribonucleotides dephosphorylation (3/3 steps found)
• dZTP biosynthesis (3/5 steps found)
• tunicamycin biosynthesis (2/9 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism
• Pantothenate and CoA biosynthesis
• Purine metabolism
• Riboflavin metabolism
• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.9

Sequence Analysis Tools

See A0A285BAJ4 at UniProt or InterPro

Protein Sequence (193 amino acids)

>BWI76_RS25485 septum formation protein Maf (Klebsiella michiganensis M5al)
MTTLYLASGSPRRQELLTQLGLAFERVVPGIEELRRPQESAQQYVVRLAREKAQAGVALA
PLDLPVLGADTIVILNGDVLEKPRDAGHAAEMLRMLSGKTHQVMTAVALADKQQTLDCLV
VTEVTFRVLSVQDIADYVASGEPLDKAGAYGIQGLGGCFVRKINGSYHAVVGLPLVETYE
LLSNFNSLREEKG