Protein Info for BWI76_RS24980 in Klebsiella michiganensis M5al

Annotation: LLM class flavin-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 53 to 67 (15 residues), see Phobius details PF00296: Bac_luciferase" amino acids 8 to 302 (295 residues), 132.7 bits, see alignment E=9.8e-43 TIGR03558: luciferase family oxidoreductase, group 1" amino acids 8 to 328 (321 residues), 442.9 bits, see alignment E=3.6e-137

Best Hits

Swiss-Prot: 91% identical to YHBW_ECOLI: Luciferase-like monooxygenase (yhbW) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to enc:ECL_04542)

Predicted SEED Role

"Luciferase-like monooxygenase (EC 1.14.-.-)" (EC 1.14.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.14.-.-

Use Curated BLAST to search for 1.14.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285BA28 at UniProt or InterPro

Protein Sequence (335 amino acids)

>BWI76_RS24980 LLM class flavin-dependent oxidoreductase (Klebsiella michiganensis M5al)
MTDKPVSFSVLDLAPIPQGSSAKEAFSHSLDLAQLAEKRGYHRYWLAEHHNMVGIASAAT
SVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLYPGRIDLGLGRAPGSDQPT
MRALRRHMSGDVDNFPRDVAELVDWFDARDPNPHVRPVPGYGEKIPVWLLGSSLYSAQLA
AQLGLPFAFASHFAPDMLFQALHLYRTHFQPSERLEKPYAMVCINIIAADSDRDAEFLFT
SVQQAFVKLRRGETGQLPPPVQNMHQLWSASEQYGVQKALSMSLVGDKTKIRHGLESILR
ETQADEIMVNGQIFDHQARLHSFDLAMQVKEALLG