Protein Info for BWI76_RS24695 in Klebsiella michiganensis M5al

Annotation: glycoside hydrolase 43 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 547 PF04616: Glyco_hydro_43" amino acids 2 to 313 (312 residues), 281.9 bits, see alignment E=6e-88 PF17851: GH43_C2" amino acids 342 to 539 (198 residues), 157.3 bits, see alignment E=4.5e-50

Best Hits

KEGG orthology group: None (inferred from 90% identity to kva:Kvar_0586)

Predicted SEED Role

"Beta-xylosidase (EC 3.2.1.37)" in subsystem Xylose utilization (EC 3.2.1.37)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.37

Use Curated BLAST to search for 3.2.1.37

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B9Q1 at UniProt or InterPro

Protein Sequence (547 amino acids)

>BWI76_RS24695 glycoside hydrolase 43 family protein (Klebsiella michiganensis M5al)
MIQNPVFRGFNPDPSICRRGDDYYVAVSSFEWFPGLPIYHSRDLKHWQLLTHVLTDDNNP
DLKKLPSAKGIWAPSLTWCEEEKLFYVIYGVMNSMNSRYFDVDNYLITASEITGPWSEPV
YLHSAGFDASILHDSDGKKWIVSLEWETREGYEKPGAICLVEYSPQRQRVVGYPQRIWRG
GTDRGCIEAPHLTRRGDYYYLMVAEGGTGYGHAVTMARATQVAGPYEGDPQNPIVTAWPE
NFNERHDAGHLKPHYFNPQTYLQKAGHGSYVETPTGEVWLTHLCSRPFRQELRCPLGRET
AIQKMIWSDDGWLRLAAGGNLAQHQVEESNLPSQPFPAKPDRDDFDGQTLDNAFYAPRIR
FQRFTSLERKAGYLALRGQESLSSLNKVSLLAKKLTSVYATIVTKMDFSPEIYQHSAGLV
LYYDNMNYLFLHKTWDEASGAAQLAIIYMDNGERHDDPQKILLATGEVYLAMAINGREIR
CSWSVDGEKYQHIGAVYDTSRFSDEYSRYGEFTGAFVGMACVDSMLHRKEALFDFFSYRA
VEDAIIE