Protein Info for BWI76_RS24495 in Klebsiella michiganensis M5al
Annotation: urease accessory protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 78% identical to URED_KLEP7: Urease accessory protein UreD (ureD) from Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
KEGG orthology group: K03190, urease accessory protein (inferred from 82% identity to eoj:ECO26_1279)Predicted SEED Role
"Urease accessory protein UreD" in subsystem Urea decomposition
MetaCyc Pathways
- superpathway of allantoin degradation in plants (7/8 steps found)
- urea degradation II (1/1 steps found)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B9I2 at UniProt or InterPro
Protein Sequence (274 amino acids)
>BWI76_RS24495 urease accessory protein (Klebsiella michiganensis M5al) MHGTVLAQNKKGWQATLDLQFQFLGGKTTLASRRHVGPLTVQRPFYPEAETCHLYLLHPP GGIVGGDELTISATIDADCHTLITMPGASKFYRSSGAQARLQQTLTLAENSTLEWLPQDA IFFPGANAALSTAFHLAASSTLLAWDLLCLGRPVIGEAFSHGALANRLEVWVDGSPLLIE RLSLADGQLACVAQQPWVGTMLFYPANETLLEGVREKLTPLANYAGATLTDGLLTVRFLS DDNLLCQRAMRDIWQFMRPHLTGKSPVLPRIWLT