Protein Info for BWI76_RS23680 in Klebsiella michiganensis M5al

Annotation: ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 4 to 292 (289 residues), 211.3 bits, E=2.2e-66
• PF08543: Phos_pyr_kin
  • amino acids 149 to 287 (139 residues), 56.8 bits, E=2.3e-19

Best Hits

KEGG orthology group: None (inferred from 91% identity to kpu:KP1_2751)

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (3/3 steps found)
• ribose phosphorylation (2/2 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.15

Use Curated BLAST to search for 2.7.1.15

Sequence Analysis Tools

See A0A285B914 at UniProt or InterPro

Protein Sequence (313 amino acids)

>BWI76_RS23680 ribokinase (Klebsiella michiganensis M5al)
MSGKVCVFGSFNFDMVARVERFPVPGESLVACGSMTSAGGKGANQATAALKAGANVHYIG
KIGNDTFGHFARRHLKGVGFNAVTLLVAEDIPTGNALIYVAGNDAENMIAVDPGANMTVS
DDEIAGCVPAIGCADVVLVQLENNLSAIERVVDAAKAAGAFVVLNPAPWQPVDNAFLSKV
DLLTPNATEAGLMTGCQVDSLAAAAEAADALHAQGARNVIITLGAKGALLSEQGVKSPIP
CFPSHPRDTTGAGDAFNGALAARLACGEPLHTAARFAAAYAAVSVEKQGASSLPDYEEAR
ERLLRAASDYEMA