Protein Info for BWI76_RS23570 in Klebsiella michiganensis M5al

Annotation: fimbrial protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 878 signal peptide" amino acids 24 to 25 (2 residues), see Phobius details transmembrane" amino acids 26 to 43 (18 residues), see Phobius details PF13954: PapC_N" amino acids 48 to 192 (145 residues), 163.3 bits, see alignment E=5.7e-52 PF00577: Usher" amino acids 208 to 790 (583 residues), 730.4 bits, see alignment E=2.5e-223 PF13953: PapC_C" amino acids 799 to 863 (65 residues), 75.7 bits, see alignment 3.1e-25

Best Hits

Swiss-Prot: 78% identical to FIMD_ECOLI: Outer membrane usher protein FimD (fimD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 87% identity to eae:EAE_02425)

Predicted SEED Role

"type 1 fimbriae anchoring protein FimD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (878 amino acids)

>BWI76_RS23570 fimbrial protein (Klebsiella michiganensis M5al)
MSHLKYGLDDLDSERKSSHGPGNTRAFAQITLALLLAAPIFSVQAELYFNPRFLADDPAA
VADLSGFASGQEVPPGTYRVDIYLNDGFMTTRDVTFNSGENDRSLVPCLTRGQLASMGVN
TLSIEGIGALASDACVPLTKTIKDATTRFDVGLQRLYLTVPQAFMGNRARGYIPPELWDH
GINAGLLNYNFTGNNVHNDVGGSSNYAYLNLQSGLNLGAWRLRDNTTWSYSSGGSSSTSE
NKWQHINTWLERDITLLRSRLTLGDSYTNGDVFDGINFRGAQLASDDNMLPDSQKGFAPV
IHGIARGTAQVSVKQNGYEIYQSTVPPGPFTINDLYSAGNGGDLQVTIKEADGSSQVFTV
PYSSVPVLQREGHTRYAVTAGEYRSGNDRQDKPKFFQSTVMRGLPGGWTLYGGTQLADRY
RAFNLGVGKNMGELGALSLDITQANATLPDDSERQGQSVRFLYNKSLTDTGTNIQLVGYR
YSTRGYFSFADTTYSRMSGYNVETQDGVMQMKPKFTDYYNLAYNKRGKVQLSVTQQLGRT
ATLYLSGSHQTYWGTNSADQQLQAGLNAAVDDINWTLSYSLTKNAWQQGRDQMLALNISI
PFSHWMRSDSTSAWRNGNASYSMSNDLNGRTTSLAGLYGTLLEDNNLSYSVQTGYAGGGD
GNSGGTGYAALNYRGGYGNANVGYSRSDGIKQLYYGLSGGVLAHADGITLSQPMNDTVVL
IKAPGADGVKVENQTGVRTDWRGYAVLPYATEYRENRVALNTNTLANNVDLDDAVVSIVP
THGAIARAEFKASVGMKLLMTLTHNGKPVPFGAIAAAVDSQNSSIVADNGQVYLSGMPMA
GKVRAKWGDGPDASCEADYRLPPESQNQALSQLSAACR