Protein Info for BWI76_RS23565 in Klebsiella michiganensis M5al

Annotation: molecular chaperone FimC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF00345: PapD_N" amino acids 37 to 156 (120 residues), 130.4 bits, see alignment E=3.8e-42 PF02753: PapD_C" amino acids 180 to 233 (54 residues), 41.4 bits, see alignment E=1.4e-14

Best Hits

Swiss-Prot: 83% identical to FIMC_ECOL6: Chaperone protein FimC (fimC) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K07346, fimbrial chaperone protein (inferred from 85% identity to cko:CKO_03710)

Predicted SEED Role

"chaperone FimC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B7V5 at UniProt or InterPro

Protein Sequence (241 amino acids)

>BWI76_RS23565 molecular chaperone FimC (Klebsiella michiganensis M5al)
MTIKGVNVRTTRAITRGLLAGALMIATMGFTARAEAGVALGATRVIYPAGQKQVQLAVTN
NDGKSTYLIQSWVENADGAKDGRFVITPPLFAMQGKKENTLRIIDATNNQLPQDRETLFW
MNVKAIPSMDKSKLSDNTLQLAIISRIKLYYRPAKLALPPDQAAEKLRFRRGAGTLTLIN
PTPYYLTVTELNAGTRVLENALVPPMGEASVKLPADAGREITYRTINDYGALTPRIQGAT
Q