Protein Info for BWI76_RS23395 in Klebsiella michiganensis M5al

Annotation: sugar ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13416: SBP_bac_8" amino acids 45 to 342 (298 residues), 77.4 bits, see alignment E=1.7e-25 PF01547: SBP_bac_1" amino acids 45 to 331 (287 residues), 118.5 bits, see alignment E=6.2e-38

Best Hits

KEGG orthology group: K10192, oligogalacturonide transport system substrate-binding protein (inferred from 92% identity to enc:ECL_04173)

Predicted SEED Role

"Sugar-binding protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B860 at UniProt or InterPro

Protein Sequence (428 amino acids)

>BWI76_RS23395 sugar ABC transporter substrate-binding protein (Klebsiella michiganensis M5al)
MKKVLLSAAISATLALTALPSMAKDVDLRMSWWGGNGRHQVTLKALEEFHKLNPDINVKA
EYTGWDGHLSRLTTQIAGGTEPDVMQTNWNWLPIFSKNGEGFYDLNKMKDVIDLSQFDAK
ELQSTTVDGKLNGIPISVTARVFYFNDETWKKAGVEYPKTWDELMAAGKTFESKLGKQYY
PVVLEHQDTLALLNSYMIQKYNQPAIDEKTKKFSYSKEQWVEFFQMYKKLIDSHVMPDTK
YYASFGKSNMYEMKPWIQGEWAGTYMWNSTINKYSDNLKPPAKLELGSYPMLPGATDAGL
FFKPAQMLSIGKSTKNPEAAAKVINFLLNSKEGVETLGLERGVPLSKVAVQYLTENGAIK
EDDPAVSGLRLAQSLPAKLSVSPYFDDPQIVAQFGTSLQYIDYGQKTVEETAIDFQRQSD
RILRRAMR