Protein Info for BWI76_RS23310 in Klebsiella michiganensis M5al

Annotation: lysophospholipid transporter LplT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 transmembrane" amino acids 16 to 41 (26 residues), see Phobius details amino acids 53 to 70 (18 residues), see Phobius details amino acids 90 to 116 (27 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details amino acids 164 to 184 (21 residues), see Phobius details amino acids 222 to 245 (24 residues), see Phobius details amino acids 257 to 277 (21 residues), see Phobius details amino acids 285 to 302 (18 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 342 to 365 (24 residues), see Phobius details amino acids 368 to 393 (26 residues), see Phobius details PF07690: MFS_1" amino acids 20 to 353 (334 residues), 68.7 bits, see alignment E=2.2e-23

Best Hits

Swiss-Prot: 93% identical to LPLT_KLEP7: Lysophospholipid transporter LplT (lplT) from Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)

KEGG orthology group: K08227, MFS transporter, LPLT family, lysophospholipid transporter (inferred from 93% identity to kpu:KP1_4516)

MetaCyc: 83% identical to lysophospholipid transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-294; TRANS-RXN-295; TRANS-RXN-387

Predicted SEED Role

"Lysophospholipid transporter LplT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B7R1 at UniProt or InterPro

Protein Sequence (397 amino acids)

>BWI76_RS23310 lysophospholipid transporter LplT (Klebsiella michiganensis M5al)
MSESVHTNGSLYSKGMMAVICAQFLSAFGDNALLFATLALMKQLFYPEWSQPVLQMLFVG
AYILFAPFVGQFADSFAKGRVMMAANGLKLVGAGCICFGVNPFIGYTLVGIGAAAYSPAK
YGILGELTTGDKLVKANGLMESSTIAAILLGSMAGGILADWHVVAALSVCAVVYAGAVVA
NLWIPKLPAARPGQSWRFRPMTHSFFSACTTLWRNGETRFSLVGTSLFWGAGVTLRFLLV
LWVPVALGITSNAMPTYLNAMVAVGIVLGAGAAAKLVTLETVSRCMPAGILIGVAVIFFA
IQQALLPAFALLLLLGAFGGFFIVPLNALLQERGKHTVGAGNAIAVQNLGENVAMLLMLG
LYSLAVSIGIPVVGVGIGFGTVFALAIAALWIWGRRK