Protein Info for BWI76_RS23100 in Klebsiella michiganensis M5al

Annotation: aquaporin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 266 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 37 to 57 (21 residues), see Phobius details amino acids 62 to 79 (18 residues), see Phobius details amino acids 85 to 106 (22 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 176 to 199 (24 residues), see Phobius details amino acids 229 to 252 (24 residues), see Phobius details PF00230: MIP" amino acids 6 to 249 (244 residues), 201.8 bits, see alignment E=6.5e-64 TIGR00861: MIP family channel proteins" amino acids 11 to 249 (239 residues), 222.9 bits, see alignment E=2.4e-70

Best Hits

Swiss-Prot: 87% identical to PDUF_SALTY: Propanediol diffusion facilitator (pduF) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 88% identity to cko:CKO_00799)

MetaCyc: 68% identical to glycerol facilitator (Escherichia coli K-12 substr. MG1655)
RXN0-7189; RXN0-7191; TRANS-RXN-131; TRANS-RXN0-460; TRANS-RXN0-536; TRANS-RXN0-537; TRANS-RXN0-551

Predicted SEED Role

No annotation

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B7P3 at UniProt or InterPro

Protein Sequence (266 amino acids)

>BWI76_RS23100 aquaporin (Klebsiella michiganensis M5al)
MNDSLKAQCTAEFLGTGLFLFFGIGCLSALKVAGASLGLWEICIIWGLGISLAVYLTSGI
SGGHLNPAVTVALWLFACFPGRKVFPYIVSQVAGAFGGAVLAYVLYSTMFTEFESAHHIA
RGSVESLQLASIFSTYPAASLSIWHAALVEVVITSMLMGMIMALTDDGNGVPKGPLAPLL
IGLLVAVIGASTGPLTGFAMNPARDFGPKLFTWMAGWGDIAMTGGRDIPYFIVPIIAPLI
GACLGAAIYRYLIGNNLPCNTCKLED