Protein Info for BWI76_RS22725 in Klebsiella michiganensis M5al

Annotation: type I-E CRISPR-associated protein Cas6/Cse3/CasE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 TIGR01907: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI" amino acids 1 to 212 (212 residues), 245.5 bits, see alignment E=3.3e-77 PF08798: CRISPR_assoc" amino acids 1 to 212 (212 residues), 164 bits, see alignment E=3.3e-52

Best Hits

KEGG orthology group: None (inferred from 79% identity to set:SEN2778)

Predicted SEED Role

"CRISPR-associated protein, Cse3 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AXQ4 at UniProt or InterPro

Protein Sequence (216 amino acids)

>BWI76_RS22725 type I-E CRISPR-associated protein Cas6/Cse3/CasE (Klebsiella michiganensis M5al)
MYLAKITLHTSQLLPSQLLQLVDRGEYAMHQWLWELFPEGPERQFLYRREELQGAFRFFV
LSLEPPAESEIFDIQYRPFAPTLIAGQTLCFSLRANPTICKGGKRHDLLMEAKRQVRGQV
NGPDMWLHQQQAAQGWLARQGEQNGFSLREVNVDAYRQQQVVRVKSRQMIQFSSVDYSGV
LVVNEPTLFLQRLIQGYGKSRAFGCGLMLIKPGDDE