Protein Info for BWI76_RS22625 in Klebsiella michiganensis M5al

Annotation: transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 139 PF12802: MarR_2" amino acids 28 to 86 (59 residues), 40.6 bits, see alignment E=3.4e-14 PF01047: MarR" amino acids 29 to 85 (57 residues), 53.3 bits, see alignment E=3.1e-18 PF13463: HTH_27" amino acids 29 to 95 (67 residues), 29.3 bits, see alignment E=1.3e-10

Best Hits

Swiss-Prot: 77% identical to HOSA_ECO11: Transcriptional regulator HosA (hosA) from Escherichia coli O111:H-

KEGG orthology group: None (inferred from 84% identity to kpu:KP1_4369)

Predicted SEED Role

"Transcriptional regulator, MarR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AXJ5 at UniProt or InterPro

Protein Sequence (139 amino acids)

>BWI76_RS22625 transcriptional regulator (Klebsiella michiganensis M5al)
MELKNEAFHLLRQLFQQHTARWQLELPDLTKPQYAVMRSIAEHPGIEQVTLTEAAVSTKA
TLAEMLSRMESRGLVRREHDPADKRRRFVYLTAEGEALLASSMPLGHAVDEEFLGRLSDE
ERQQFSQIIHKLMAQEQQR