Protein Info for BWI76_RS22425 in Klebsiella michiganensis M5al

Annotation: metal ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01297: ZnuA" amino acids 32 to 295 (264 residues), 270.4 bits, see alignment E=8.2e-85

Best Hits

Swiss-Prot: 67% identical to Y362_HAEIN: Uncharacterized periplasmic iron-binding protein HI_0362 (HI_0362) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 93% identity to eae:EAE_01710)

Predicted SEED Role

"Manganese ABC transporter, periplasmic-binding protein SitA" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AXF9 at UniProt or InterPro

Protein Sequence (305 amino acids)

>BWI76_RS22425 metal ABC transporter substrate-binding protein (Klebsiella michiganensis M5al)
MLHLPPLKHLMFAATLALLAVAPVQAKEKFKVITTFTVIADMAQNVAGDAADVSSITKPG
AEIHEYQPTPGDIKRAQGAQLILANGLNLELWFARFYQHLNGVPEVVVSNGIQPMGISEG
PYNGKPNPHAWMSADNALIYVDNIRDALVKYDPENADAYRHNAETYKEKIRQTMTPLKAE
LAKLPQDKRWLVTSEGAFSYLARDNGLQELYLWPINADQQGTPQQVRKTIDTMKKAHIPT
IFSESTISDKPARQVAREAGAHYGGVLYVDSLSAADGPVPTYLDLLRVTTQTIVQGINDG
LRKQA