Protein Info for BWI76_RS22385 in Klebsiella michiganensis M5al

Annotation: beta-1,4 mannanase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 731 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF16990: CBM_35" amino acids 610 to 730 (121 residues), 134.6 bits, see alignment E=1.1e-43

Best Hits

KEGG orthology group: None (inferred from 82% identity to kva:Kvar_0996)

Predicted SEED Role

"Endo-b1,4-mannanase 5C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AXE5 at UniProt or InterPro

Protein Sequence (731 amino acids)

>BWI76_RS22385 beta-1,4 mannanase (Klebsiella michiganensis M5al)
MIKPVTKLMLVALLSALGSAGAMAAERSHFEHFITRDGATLKDGDKVFRFAGIHAPELHR
IEDDARGTCKADTRGWGQYFRWPTAEEQENWIKAMVQTGARAQRVYVLSVQQTFDEACGR
ETHILAPETTDGMPRLNEKAMRVYDNMIAEADKQGLRLILPFIDHWWWWGGREQLAAFYH
EKPEDFYRTDSKTFKAYLDVIRQVITRTNSVTGRPYFDEKAIMAWETGNELEDTNAAFLQ
QTAAWIKKWAPHQLVVDGTYKKINGFALNDPNVDIVSNHYYTNADNNHPDQVKKDLTAAA
GKKVYMVGEFGLLDAQQLNAIMQSIVHSEVNGAQAAGGLIWGFRGHRHDGGFYWHKESTG
HYSYHLPGFPMEGKANEEMEVVDLVRTAAAQMNGQENAPPLPKPDAPTLRATDSPFAINW
LGAAVGRAYDVERADSASGPWKVVGRDISDGVNEWNPQTMDLFRDDYRSLQLGNTYYYRV
IAKNESGSSAPSNVISVKHTQANQAPVVALAETLTTSQDQGVQLSASWRDDGLPDRDVKV
NWSNGGSAQAHFCTTDKAETRAWFSAPGEYALTFSADDGLLKSSKTVKVTVTEAAGKVPA
DYCRFGGGVLHVTEGKIEAAKSEKDALTIDEDGFLGPFANDGDKVSWQVSAPWAGKYLLR
VTFSGKWGGKKNSFIVNGGAPIAVEFPQTDEQGQQQLVPVELKAGDNRIDFGKFAGDWGY
MFIKSIEVVAE