Protein Info for BWI76_RS21965 in Klebsiella michiganensis M5al

Annotation: export and assembly usher protein of type 1 fimbriae

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 844 signal peptide" amino acids 1 to 41 (41 residues), see Phobius details PF13954: PapC_N" amino acids 43 to 188 (146 residues), 149.7 bits, see alignment E=8.7e-48 PF00577: Usher" amino acids 203 to 746 (544 residues), 620.2 bits, see alignment E=5.9e-190 PF13953: PapC_C" amino acids 756 to 826 (71 residues), 55.5 bits, see alignment E=6.3e-19

Best Hits

KEGG orthology group: K07347, outer membrane usher protein (inferred from 77% identity to kva:Kvar_1082)

Predicted SEED Role

"type 1 fimbriae anchoring protein FimD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AX70 at UniProt or InterPro

Protein Sequence (844 amino acids)

>BWI76_RS21965 export and assembly usher protein of type 1 fimbriae (Klebsiella michiganensis M5al)
MKNNTSDMTSVYSAIAAPTGGIFLLPTAIFLLCQSGIARAEDYFDPAALEFANPQQKTAD
LHYFAKSGGQQPGTYPVSIWVNNQEIAQSEVTFVDSNGALQPQLTPAQLAEYGVNVSAFP
AFNTLHEGEPFTHIERYIPDASSRFDFATQRLNLSIPQAAMNVQSRGYVDPARWDEGIPA
AFVNYNLTGSQTRQSDDNSRSSYLNLRSGVNFGAWRLRNVSSMEYDRTRRWNSQSTWLQR
DLKSLKSLLRMGDTFTSGDVFDSVQFRGVQLMSDDEMLPDSQRGFAPTIRGMAHSNAKVT
ISQHGYVIYETFVSPGAFAISDLYPTAQSGDLEVQVKESDGSVRTFTQPFSAVPFMLREG
RVKFSLSAGRYHSGQSRTPSPTFLQGTLFYGLPAEFTLYGGSQLAQDYQSWALGVGRGFG
ELGSLGGDATWANTTTPSGKRSAGHSLRVQYQKDFAGTGTSFSLASYRYSSGGYYDFSEA
NALESRNGLVDNKRSREEISVSQAFGGMSSLAISAWSQEYWHRQSRDETIHLGFYSAWRG
VSWGVGYYYTQSSDRQKADRSWSFNLSIPLGGPLAESAISYSTTSGNNGRTSQQASLYGS
IPRNPNLYYSLQQGYANGGQGSNSSASLDYHGGYGTAQLGYRQDSASHQLTWGASGSIVA
HPHGVTLGQTVGESFAIVRAPGAADVAIQNGSNVHTDWRGYAVVPSLTAYRKNTITLDTE
SLADDADVELEGQTVIPGGGAVVQANYQTHIGNRVLFTLSDSRGPLPFGASVRLRKAEDE
QGAAPGGMVADGGQVYLSGIPQEGTLDVAWNADNISRKCALHFHLTDTVQQGQSPVKTVS
GVCQ