Protein Info for BWI76_RS21940 in Klebsiella michiganensis M5al

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF23441: SDR" amino acids 9 to 253 (245 residues), 56.9 bits, see alignment E=4.5e-19 PF00106: adh_short" amino acids 9 to 196 (188 residues), 147.3 bits, see alignment E=8e-47 PF08659: KR" amino acids 11 to 113 (103 residues), 42.8 bits, see alignment E=1.2e-14 PF13561: adh_short_C2" amino acids 16 to 252 (237 residues), 185.3 bits, see alignment E=2.8e-58

Best Hits

KEGG orthology group: None (inferred from 65% identity to bam:Bamb_6448)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285AX72 at UniProt or InterPro

Protein Sequence (258 amino acids)

>BWI76_RS21940 SDR family oxidoreductase (Klebsiella michiganensis M5al)
MNTTFMGKKLLVVGGTSGMGLATAKRVVENGGSVVLVGNRREKAERARQALAAAGKVDVI
VADLTSEAGMQQVMANINAEHQDISLLVNAAGVFFPKPFIEHEMADYDRYMHLNRATFFI
TREVVRNMLANGIKGSIVNIGSMWAQQAIGATPSSAYSMAKAGLHALTKNLAIELGGSGI
RVNAVSPAVVHTPIYEGFIPEEDVKAVMNSFDGFHPIGRVGTPDDIAQTVAFLLSESTRW
VTGAVWDIDGGVMAGRNA