Protein Info for BWI76_RS21805 in Klebsiella michiganensis M5al

Annotation: sodium-independent anion transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 492 transmembrane" amino acids 19 to 39 (21 residues), see Phobius details amino acids 46 to 67 (22 residues), see Phobius details amino acids 87 to 107 (21 residues), see Phobius details amino acids 119 to 137 (19 residues), see Phobius details amino acids 143 to 161 (19 residues), see Phobius details amino acids 168 to 187 (20 residues), see Phobius details amino acids 216 to 239 (24 residues), see Phobius details amino acids 261 to 282 (22 residues), see Phobius details amino acids 291 to 309 (19 residues), see Phobius details amino acids 317 to 338 (22 residues), see Phobius details amino acids 350 to 378 (29 residues), see Phobius details PF00916: Sulfate_transp" amino acids 15 to 144 (130 residues), 105.2 bits, see alignment E=3.4e-34 amino acids 150 to 353 (204 residues), 107.7 bits, see alignment E=5.9e-35 PF01740: STAS" amino acids 393 to 482 (90 residues), 54.4 bits, see alignment E=9.6e-19

Best Hits

Swiss-Prot: 57% identical to YBAR_BACSU: Putative sulfate transporter YbaR (ybaR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 96% identity to enc:ECL_00479)

Predicted SEED Role

"Sulfate permease" in subsystem Cysteine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (492 amino acids)

>BWI76_RS21805 sodium-independent anion transporter (Klebsiella michiganensis M5al)
MLLSSTRKDWLGNVRGDVLAGIVVALALIPEAIAFSIIAGVDPQVGLYSAFCIPLIMAFF
GGRPAMISSSTGAMALLMVTLVKDHGLQYLLAASVLTGIFQLIAGYLKLGSLMRFVSRSV
VTGFVNALAILIFMAQLPELTNVTWHVYAMTAGGLAIIYLFPYLNKTIPSPLVCIVVLTA
IAMWLHLDVRTVGDMGKLPDSLPVFLVPDIPLNLDTLLIILPYSAGLAVVGLLESMMTAT
IVDDMTDTPSDKNRECKAQGIANICTSFIGGMAGCAMIGQSVINVKSGGRGRLSTLTAGV
VLLCMVVFLRDLVSQIPMAALVAVMIMVSIGTFSWRSVVDLKSHPVSTSVVMLATVVVVV
ATHNLAFGVLTGVLIASLNFATKVARFLAVSSELREETRIYKVTGQVFFASADRFMAYFD
FREAVEKVVIDVTHAHFWDITSVSALDKVVIKFRREGTDVEIRGMNEATRTIVDRFGVHD
KPEEVEKLMGGH