Protein Info for BWI76_RS20775 in Klebsiella michiganensis M5al

Annotation: ethanolamine utilization protein EutH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 54 to 81 (28 residues), see Phobius details amino acids 120 to 146 (27 residues), see Phobius details amino acids 153 to 178 (26 residues), see Phobius details amino acids 190 to 215 (26 residues), see Phobius details amino acids 227 to 250 (24 residues), see Phobius details amino acids 273 to 294 (22 residues), see Phobius details amino acids 342 to 363 (22 residues), see Phobius details amino acids 369 to 392 (24 residues), see Phobius details PF04346: EutH" amino acids 3 to 391 (389 residues), 432.6 bits, see alignment E=6.3e-134

Best Hits

Swiss-Prot: 93% identical to EUTH_SALTY: Ethanolamine utilization protein EutH (eutH) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K04023, ethanolamine transporter (inferred from 96% identity to esc:Entcl_1315)

Predicted SEED Role

"Ethanolamine permease" in subsystem Ethanolamine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B7D3 at UniProt or InterPro

Protein Sequence (410 amino acids)

>BWI76_RS20775 ethanolamine utilization protein EutH (Klebsiella michiganensis M5al)
MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGSGGQFEEGFMAMGALGL
AMVGMTALAPVLAHLLGPVIIPLYEMLGANPSMFAGTLLACDMGGFFLAKELAGGDVAAW
LYSGLILGAMMGPTLVFSIPVALGIIEPSDRRYLALGVLAGIVTIPIGCIAGGLVAMYSG
VEINGQPVEFTFALILMNMIPVLIVAVLVALGLKFIPEKMINGFQIFAKFLVALITIGLA
AAVIKFLLGWDLIPGLDPIFMAPGDQPGEVMRAIEVIGSISCVLLGAYPMVLLLTRWFEK
PLMRVGNLLKINNMAAGGMVATLANNIPMFGMMKQMDTRGKVINCAFSVSAAFALGDHLG
FAAANMNAMIFPMIVGKLIGGVTAIGVAMLLVPKDENVPAAAKTEAEAQS