Protein Info for BWI76_RS20675 in Klebsiella michiganensis M5al

Annotation: GMP synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 235 PF00117: GATase" amino acids 42 to 183 (142 residues), 59.7 bits, see alignment E=1.6e-20

Best Hits

Swiss-Prot: 72% identical to YFEJ_SALTY: Putative glutamine amidotransferase-like protein YfeJ (yfeJ) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 87% identity to eae:EAE_00395)

MetaCyc: 72% identical to gamma-L-glutamyl hydroxamate hydrolase (Salmonella enterica enterica serovar Typhimurium str. LT2)
RXN1R65-43

Predicted SEED Role

"Putative amidotransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B7S8 at UniProt or InterPro

Protein Sequence (235 amino acids)

>BWI76_RS20675 GMP synthase (Klebsiella michiganensis M5al)
MQIHFIVHEVFEAPGAYLRWAQARGYGISWSRVYAGDALPENANAFDMLVVLGGPQSPRT
TLTECPWFDSHAEQRLIAQAIAAGRIVVGICLGSQLIGEALGAPVMQSPEKEVGHYPITL
TTAGLQDDKLAHFGPSLVVGHWHNDMPGLTPEAEVMASSEGCPRQIVKYSDRVYGFQCHM
EFDAEVIELLIAHSQQELSAARGRRFIRSEQEMRAWDYREMNEKLWVFLDKLTAK